Gloria Oliván Rosas

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BACKGROUND Dilated cardiomyopathy is characterized by an imbalance between left ventricular performance and myocardial energy consumption. Experimental models suggest that oxidative stress resulting from increased xanthine oxidase (XO) activity contributes to this imbalance. Accordingly, we hypothesized that XO inhibition with intracoronary allopurinol(More)
Cardiovascular aging is associated with decreased endothelial vasoreactivity and prolonged diastolic relaxation. As diminished NO signaling contributes to age-associated endothelial dysfunction, we tested the hypothesis that impaired NO signaling or bioactivity also contributes to slowed ventricular relaxation with age. Accordingly, we measured myocardial(More)
Innate immunity not only mediates early host defenses to infection, but also contributes to septic hemodynamic compromise through nitric oxide synthase (NOS2) induction and inhibition of cardiovascular adrenergic responses. Because of increased age-related susceptibility to sepsis, we hypothesized that hearts from old (28-29 months) adult rats would exhibit(More)
RESUMEN Las malformaciones dentales referentes a bigeminismos, fusiones dentarias, etc. presentan una prevalencia que oscila de 0,5 a 5%, dependiendo de factores geográficos, raciales o genéticos. Ello puede comportar una modificación en el tratamiento a llevar a cabo en cada caso particular. La presencia de anomalias en la forma, tamaño y número de dientes(More)
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