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The relationship between corneal edema and hydrogel lens oxygen transmissibility was examined for both daily and extended contact lens wear by measuring the corneal swelling response induced by a variety of contact lenses over a 36-hr wearing period. The relationships derived enable average edema levels that occur with daily and extended wear in a… (More)
The overnight corneal swelling of nine subjects was measured with an electronic digital pachometer. Corneal thickness measurements were taken just before eye closure and after seven hours of sleep. Post-sleep recovery to original corneal thickness was followed. Results showed overnight corneal swelling to be about 4 1/2% with logarithmic recovery to… (More)
Recent reports suggest that the aphakic eye develops less corneal edema than the phakic eye during hydrogel contact lens wear. Measurements were made of several ocular characteristics that might account for this difference in nine unilateral aphakic subjects. The measurements showed that compared with the phakic eye, the aphakic eye averaged a 15% lower… (More)
PURPOSE To determine the clinical performance of daily disposable contact lens wear compared to conventional daily wear contact lenses and frequent replacement contact lenses. METHODS This 3-year prospective study was conducted in 12 U.S. practices. Of 338 eligible subjects enrolled (126 conventional daily wear, 144 frequent replacement, and 68 daily… (More)
Corneal thickness changes were monitored across the cornea in 10 subjects during 7 days continuous wear of 3 types of hydrogel contact lenses of different back vertex powers. Analysis of topographical corneal thickness changes indicates that the periphery of the cornea swells significantly less than the central cornea. The effect is more dramatic with… (More)
The plasma endotoxin levels of 16 severely malnourished Thai children were determined by the Limulus amebocyte lysate assay. Endotoxemia was present in seven children (44%) on admission to the hospital and was associated with the coexistence of vitamin A deficiency. Protein-energy malnutrition is associated with the presence of endotoxemia.
A 3-month clinical investigation was undertaken to evaluate a population of premium reusable daily wear soft contact lens wearers when refitted with soft contact lenses worn on a daily wear schedule and replaced every 2 weeks. In addition to an initial visit, follow-up visits occurred at 2-, 4-, 8-, and 12 weeks. Areas of assessment included vision, lens… (More)