Glenn L. Martin Hall

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We explore the rate-dependent dynamic response of periodically paced bullfrog (Rana catesbeiana) cardiac muscle. Alternans (2:2 behavior) occur in 35% of animals and 2:1 $ 1:1 bistability in 74% of animals. In addition, we observe 2:2 $ 2:1 bistablility. We discuss the implications of these results for two map-based models of cardiac dynamics. The high(More)
The processes of anaesthesia and surgery attenuate normal homeostatic thermoregulation and impose large thermal stresses. The resulting changes in body temperature may be detrimental and it is important, therefore, that anaesthetists understand normal thermoregulation and the ways in which this process may be affected by anaesthesia. Why thermoregulate ?(More)
Six subjects susceptible to malignant hyperthermia (MHS) and seven control subjects exercised for 4 min at 120% of their calculated maximal oxygen uptake on a bicycle ergometer. Mean (SEM) muscle pH, measured with a needle-tipped electrode in the vastus lateralis muscle, decreased from a resting value of 7.16 (0.04) to 6.78 (0.04) after exercise in the(More)
We studied the effects of supplementing nitrous oxide-oxygen anaesthesia with halothane (1 MAC end-tidal concentration) on the motor evoked potential recorded in the extradural space of eight patients before corrective surgery for idiopathic adolescent scoliosis. The motor cortex was stimulated electrically through the scalp. An additional eight patients in(More)
Parkinson's disease is an increasingly common disease of elderly patients who present a particular anaesthetic challenge. This review explores the epidemiology, aetiology, pathogenesis, and pathophysiology of the condition, particularly the possible role of genetic factors. The clinical features are described in detail and recent advances in medical(More)
The contributions of aerobic and anaerobic muscle metabolism to the heat produced in porcine malignant hyperthermia were studied in seven Pietrain pigs. Oxygen consumption measurements were used to calculate the increase in muscle temperature as a result of aerobic metabolism and this was compared with the observed muscle temperature. The results show that(More)
To determine the site of action of fentanyl in attenuating the pituitary-adrenal response to surgery, we have measured serum concentrations of cortisol and growth hormone during and after a standardized surgical procedure in two groups of patients. One group received fentanyl 15 micrograms kg-1 i.v. immediately before the start of surgery; a second group(More)
A large-scale of civil infrastructure systems is associated with great amounts of project resources and activities interoperated with various participants and organizations. Well-defined methodology for information acquisition and communication became more critical in the management of civil infrastructure than ever before. Rapidly emerging wireless sensor(More)