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BACKGROUND The current risk assessment for environmental cadmium (Cd) largely relies on the assumption that urinary Cd (U-Cd) is a reliable biomarker of the Cd body burden. Recent studies have questioned the validity of this assumption. OBJECTIVES We studied the lifetime trend of U-Cd as a function of diuresis, gender, smoking status, and protein tubular(More)
BACKGROUND Trypanosomes can synthesize polyunsaturated fatty acids. Previously, we have shown that they possess stearoyl-CoA desaturase (SCD) and oleate desaturase (OD) to convert stearate (C18) into oleate (C18:1) and linoleate (C18:2), respectively. Here we examine if OD is essential to these parasites. METHODOLOGY Cultured procyclic (insect-stage) form(More)
BACKGROUND Some but not all studies have reported abnormal polyunsaturated fatty acid composition in cystic fibrosis (CF) patients. We investigated the influence of pancreatic status and sex on the fatty acid profile in plasma and erythrocyte membranes in patients with CF. METHODS After a 1-step transesterification with acetyl chloride on plasma and(More)
Carman. 2011b. Population exposure to a novel influenza A virus over three waves of infection. 2011. The best practice for preparation of samples from FTA(R)cards for diagnosis of blood borne infections using African trypanosomes as a model system. Host inhibits replication of European porcine reproductive and respiratory syndrome virus in macrophages by(More)
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