Giuseppina Sidoli

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STATEMENT OF PROBLEM A self-contained post and core system, Composipost, comprising an epoxy-based carbon fiber post, a composite core material, and a low viscosity Bis-GMA bonding resin, has recently been marketed for the restoration of pulpless teeth. PURPOSE This study compared the in vitro performance and the failure characteristics of the Composipost(More)
Poly(ADP-ribose) polymerase-1 (PARP-1) uses NAD(+) as a substrate to form ADP-ribose. During apoptosis, caspases cleave PARP-1 to avoid excessive NAD consumption. Because PARP-1 is a key regulator of the activity of DNases involved in caspase-dependent apoptosis, its cleavage is required to promote DNA degradation. To explore the situation in(More)
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