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Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease.

• Misha Zilberter, Anton Ivanov, +11 authors Yuri Zilberter
• Journal of neurochemistry
• 2013

Deficient energy metabolism and network hyperactivity are the early symptoms of Alzheimer's disease (AD). In this study, we show that administration of exogenous oxidative energy substrates (OES)… (More)

Secretagogin is a Ca2+-binding protein specifying subpopulations of telencephalic neurons.

• Jan Mulder, Misha Zilberter, +6 authors Tibor Harkany
• Proceedings of the National Academy of Sciences…
• 2009

The Ca(2+)-binding proteins (CBPs) parvalbumin, calbindin, and calretinin are phenotypic markers of terminally differentiated neurons in the adult brain. Although subtle phylogenetic variations in… (More)

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding.

• Erik Keimpema, Kornélia Barabás, +7 authors Tibor Harkany
• The Journal of neuroscience : the official…
• 2010

Endocannabinoids, particularly 2-arachidonoyl glycerol (2-AG), impact the directional turning and motility of a developing axon by activating CB(1) cannabinoid receptors (CB(1)Rs) in its growth cone.… (More)

Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.

• Ming-Dong Zhang, Giuseppe Tortoriello, +12 authors Tomas G M Hökfelt
• Proceedings of the National Academy of Sciences…
• 2014

Neuronal calcium (Ca(2+))-binding proteins 1 and 2 (NECAB1/2) are members of the phylogenetically conserved EF-hand Ca(2+)-binding protein superfamily. To date, NECABs have been explored only to a… (More)

Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon.

• Jan Mulder, Lauren Spence, +9 authors Tibor Harkany
• The European journal of neuroscience
• 2010

The Ca(2+)-binding proteins (CBPs) calbindin D28k, calretinin and parvalbumin are phenotypic markers of functionally diverse subclasses of neurons in the adult brain. The developmental dynamics of… (More)

Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway.

• Giuseppe Tortoriello, Claudia A V Morris, +10 authors Tibor Harkany
• The EMBO journal
• 2014

Children exposed in utero to cannabis present permanent neurobehavioral and cognitive impairments. Psychoactive constituents from Cannabis spp., particularly Δ(9)-tetrahydrocannabinol (THC), bind to… (More)

Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human

• T S Shi, Qiong Xiang, +9 authors Tomas G M Hökfelt
• Molecular pain
• 2012

BACKGROUND Secretagogin (Scgn), a member of the EF-hand calcium-binding protein (CaBP) superfamily, has recently been found in subsets of developing and adult neurons. Here, we have analyzed the… (More)

Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signaling

• Alán Alpár, Giuseppe Tortoriello, +14 authors Tibor Harkany
• Nature communications
• 2014

Local environmental cues are indispensable for axonal growth and guidance during brain circuit formation. Here, we combine genetic and pharmacological tools, as well as systems neuroanatomy in human… (More)

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.

• Erik Keimpema, Giuseppe Tortoriello, +8 authors Tibor Harkany
• Proceedings of the National Academy of Sciences…
• 2013

Endocannabinoid, particularly 2-arachidonoyl glycerol (2-AG), signaling has recently emerged as a molecular determinant of neuronal migration and synapse formation during cortical development.… (More)

Prevention of surgery in children with adenoidal hypertrophy treated with intranasal flunisolide: a 12-month follow-up.

• Alfonso Maria Varricchio, Giuseppe Tortoriello, +6 authors Mario Di Gioacchino
• Journal of biological regulators and homeostatic…
• 2009

Adenoidal hypertrophy (AH) represents one of the most frequent indications for surgery in children. Recently, treatment with intranasal corticosteroids has been suggested to decrease the size of AH.… (More)

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