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  • Alessandro Moretta, C. Bottino, +7 authors Ermanno Ciccone
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1990 (First Publication: 1 December 1990)
  • In previous studies we identified a surface molecule (termed GL183) capable of mediating cell activation and selectively expressed by a subset of human CD3-CD16+ natural killer (NK) cells. In thisExpand
  • Kehmia Titanji, Stefano Sammicheli, +10 authors F Chiodi
  • Biology, Medicine
  • Immunology
  • 2008 (First Publication: 11 July 2007)
  • Human natural killer (NK) (CD3- CD56+) cells can be divided into two functionally distinct subsets, CD3- CD56(dim) and CD3- CD56(bright). We analysed the distribution of NK cell subsets in primaryExpand
  • C. Bottino, Giuseppe Tambussi, +5 authors Alessandro Moretta
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1988 (First Publication: 1 August 1988)
  • Two mAbs directed to the TCR-gamma/delta were analyzed for their pattern of reactivity with CD3+WT31- cell populations or clones. In normal individuals, the BB3 mAb reacted with approximately 2/3 ofExpand
  • Alessandro Moretta, Giuseppe Tambussi, +5 authors Lorenzo Moretta
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1990 (First Publication: 1 March 1990)
  • The GL183 mAb was obtained by immunizing BALB/c mice with the E57 clone (CD7+CD2+CD3-CD16+CD56+) derived from human peripheral blood NK cells. In human peripheral blood, GL183-reactive cells rangedExpand
  • Lucinda Furci, Gabriella Scarlatti, +13 authors Alberto Beretta
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1997 (First Publication: 4 August 1997)
  • Despite repeated exposure to HIV-1, certain individuals remain persistently uninfected. Such exposed uninfected (EU) people show evidence of HIV-1–specific T cell immunity and, in rare cases,Expand
  • Paola Mantegani, Giuseppe Tambussi, Laura Galli, Chiara Tassan Din, Adriano Lazzarin, Claudio Fortis
  • Medicine, Biology
  • Immunology
  • 2010 (First Publication: 1 February 2010)
  • We investigated the distribution of natural killer (NK) cell subsets, their activating and inhibitory receptors, and their cytolytic potential, in primary human immunodeficiency virus (HIV)-infectedExpand
  • Alessandro Moretta, Ermanno Ciccone, +5 authors Maria Cristina Mingari
  • Medicine, Biology
  • International journal of cancer. Supplement…
  • 1989
  • Natural killer cells are characterized by the lack of CD3/TCR molecules and by the expression of CD16 and CD56 (NKHI or Leu19) surface antigens. In addition to their ability to lyse certain tumorExpand