Giuseppe Schettino

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hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

Derek J Richard, Kienan Savage, +9 authors Kum Kum Khanna
Nucleic acids research
2011

hSSB1 is a newly discovered single-stranded DNA (ssDNA)-binding protein that is essential for efficient DNA double-strand break signalling through ATM. However, the mechanism by which hSSB1 functions… (More)

DNA double strand break repair: a radiation perspective.

Joy N Kavanagh, Kelly Marie Redmond, Giuseppe Schettino, Kevin M Prise
Antioxidants & redox signaling
2013

SIGNIFICANCE Ionizing radiation (IR) can induce a wide range of unique deoxyribonucleic acid (DNA) lesions due to the spatiotemporal correlation of the ionization produced. Of these, DNA double… (More)

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