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  • J Gabert, Emmanuel Beillard, +17 authors J J M van Dongen
  • Biology, Medicine
  • Leukemia
  • 2003 (First Publication: 1 December 2003)
  • Detection of minimal residual disease (MRD) has proven to provide independent prognostic information for treatment stratification in several types of leukemias such as childhood acute lymphoblasticExpand
  • Timothy P Hughes, Michael Deininger, +18 authors John M. Goldman
  • Medicine
  • Blood
  • 2006 (First Publication: 1 July 2006)
  • The introduction in 1998 of imatinib mesylate (IM) revolutionized management of patients with chronic myeloid leukemia (CML) and the second generation of tyrosine kinase inhibitors may prove superiorExpand
  • Jorge E. Cortes, Giuseppe Saglio, +9 authors Andreas Hochhaus
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2016 (First Publication: 1 May 2016)
  • PURPOSE We report the 5-year analysis from the phase III Dasatinib Versus Imatinib Study in Treatment-Naïve Chronic Myeloid Leukemia Patients (DASISION) trial, evaluating long-term efficacy andExpand
  • Jjm van Dongen, Ea Macintyre, +14 authors Alberto Biondi
  • Biology, Medicine
  • Leukemia
  • 1999 (First Publication: 1 December 1999)
  • Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia patients have shown that large-scale MRD studies are feasible and that clinically relevant MRD-based riskExpand
  • Simona Soverini, Andreas Hochhaus, +11 authors Giovanni Martinelli
  • Medicine
  • Blood
  • 2011 (First Publication: 4 August 2011)
  • Mutations in the Bcr-Abl kinase domain may cause, or contribute to, resistance to tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia patients. Recommendations aimed to rationalize the useExpand