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The efficacy and safety of budesonide/formoterol in a single inhaler compared with placebo, budesonide and formoterol were evaluated in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD). In a 12-month, randomised, double-blind, placebo-controlled, parallel-group study in 812 adults (mean age 64 yrs, mean forced expiratory volume(More)
In this paper we show how we have applied, in a current project, mobile agent technology to an industrial process in the field of textile manufacturing. The project involves several companies, each of which is a Europe-wide representative of one of the key phases of the textile production process (e.g. spinning, weaving, dyeing, finishing and ready made(More)
In this paper we adopt the fluid approximation theory to describe the dynamic behavior of Flexible Manufacturing Systems that we model with Hybrid Stochastic Petri Nets, a class of nets in which some places may hold fluid rather than discrete tokens. The continuous transitions of the net are fired with speeds that are piecewise constants over the entire(More)
the two views of framework reuse, referred to as " white-box " and " black-box " approaches to reuse, are simultaneously present in one framework [9]. Features likely to be common to most applications can be offered and therefore reused as black boxes with minor changes. On the other hand, the class library accompanying the framework usually provides base(More)
The old electricity network infrastructure has proven to be inadequate, with respect to modern challenges such as alternative energy sources, electricity demand and energy saving policies. Moreover, Information and Communication Technologies (ICT) seem to have reached an adequate level of reliability and flexibility in order to support a new concept of(More)