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INTRODUCTION Asymptomatic atrial fibrillation (AF) can expose patients to the risk of stroke. The primary objective of this study was to assess the incidence of thromboembolic events in relationship with CHADS(2) (congestive heart failure, hypertension, age >or=75 years, diabetes mellitus, and prior stroke, or transient ischemic attack) score and AF(More)
CONTEXT Recently, the implantable cardioverter-defibrillator (ICD) has been promoted for prevention of sudden death in hypertrophic cardiomyopathy (HCM). However, the effectiveness and appropriate selection of patients for this therapy is incompletely resolved. OBJECTIVE To study the relationship between clinical risk profile and incidence and efficacy of(More)
BACKGROUND Phrenic stimulation (PS) may hinder left ventricular (LV) pacing. We prospectively observed its prevalence in consecutive patients with cardiac resynchronization therapy (CRT) devices. METHODS AND RESULTS In the years 2003 to 2006, 197 patients received a CRT device. PS and LV threshold measurements were carried out at implantation and at(More)
Authors/Task Force Members: Michele Brignole (Chairperson) (Italy)*, Angelo Auricchio (Switzerland), Gonzalo Baron-Esquivias (Spain), Pierre Bordachar (France), Giuseppe Boriani (Italy), Ole-A Breithardt (Germany), John Cleland (UK), Jean-Claude Deharo (France), Victoria Delgado (Netherlands), Perry M. Elliott (UK), Bulent Gorenek (Turkey), Carsten W.(More)
BACKGROUND The role of implantable cardioverter-defibrillator (ICD) in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and no prior ventricular fibrillation (VF) or sustained ventricular tachycardia is an unsolved issue. METHODS AND RESULTS We studied 106 consecutive patients (62 men and 44 women; age, 35.6±18 years) with(More)
BACKGROUND The clinical value of interventricular (V-V) delay optimization in patients with chronic congestive heart failure (CHF) undergoing implantation of a device for cardiac resynchronization therapy (CRT) has not been clearly demonstrated. METHODS RHYTHM II was a single-blind randomized trial including 121 recipients of a device for CRT with(More)
OBJECTIVE The aim of this study was to assess the association between maximum daily atrial fibrillation (AF) burden and risk of ischaemic stroke. BACKGROUND Cardiac implanted electronic devices (CIEDs) enhance detection of AF, providing a comprehensive measure of AF burden. DESIGN, SETTING, AND PATIENTS A pooled analysis of individual patient data from(More)
OBJECTIVES To investigate diagnostic routes, echocardiographic substrates, outcomes and prognostic factors in patients with isolated ventricular non-compaction (IVNC) identified by echocardiographic laboratories with referral from specialists and primary care physicians. PATIENTS AND DESIGN Since 1991, all patients with suspected IVNC were flagged and(More)
BACKGROUND New atrial pacing techniques and overdrive pacing algorithms have been introduced to prevent atrial fibrillation. This study was designed to test the hypotheses that (1) interatrial septum pacing (IASP) at the triangle of Koch would be more effective than right atrial appendage pacing (RAAP) in preventing paroxysmal atrial fibrillation (PAF) in(More)