Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

Multicolor Bioluminescence Boosts Malaria Research: Quantitative Dual-Color Assay and Single-Cell Imaging in Plasmodium falciparum Parasites

• Luca Cevenini, Grazia Camarda, +9 authors Pietro Alano
• Analytical chemistry
• 2014

New reliable and cost-effective antimalarial drug screening assays are urgently needed to identify drugs acting on different stages of the parasite Plasmodium falciparum, and particularly those… (More)

Persistence of a Large Population of Exhausted Monoclonal B cells in Mixed Cryoglobuliemia After the Eradication of Hepatitis C Virus Infection

• Marcella Visentini, Valentina Conti, +4 authors Massimo Fiorilli
• Journal of Clinical Immunology
• 2012

Functionally exhausted and mostly autoreactive B-cells with a peculiar CD21lowCD11c+ phenotype accumulate in several human immunological disorders including common variable immunodeficiency, HIV… (More)

A Molecular Assay to Quantify Male and Female Plasmodium falciparum Gametocytes: Results From 2 Randomized Controlled Trials Using Primaquine for Gametocyte Clearance.

• Will Stone, Patrick Sawa, +19 authors Teun Bousema
• The Journal of infectious diseases
• 2017

Background Single low-dose primaquine (PQ) reduces Plasmodium falciparum infectivity before it impacts gametocyte density. Here, we examined the effect of PQ on gametocyte sex ratio as a possible… (More)

A chemical susceptibility profile of the Plasmodium falciparum transmission stages by complementary cell-based gametocyte assays.

• Sarah D'Alessandro, Grazia Camarda, +8 authors Pietro Alano
• The Journal of antimicrobial chemotherapy
• 2016

OBJECTIVES As most available antimalarial drugs are ineffective against the Plasmodium falciparum transmission stages, new drugs against the parasite's gametocytes are urgently needed to combat… (More)

CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination…

• Caroline L Ng, Giulia Siciliano, +11 authors David A. Fidock
• Molecular microbiology
• 2016

Emerging resistance to first-line antimalarial combination therapies threatens malaria treatment and the global elimination campaign. Improved therapeutic strategies are required to protect existing… (More)

A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay.

• Giulia Siciliano, T R Santha Kumar, +8 authors Pietro Alano
• Molecular microbiology
• 2017

The goal to prevent Plasmodium falciparum transmission from humans to mosquitoes requires the identification of targetable metabolic processes in the mature (stage V) gametocytes, the sexual stages… (More)

Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity

• Manu Vanaerschot, Leonardo Lucantoni, +23 authors David A. Fidock
• Nature Microbiology
• 2017

Antimalarial compounds with dual therapeutic and transmission-blocking activity are desired as high-value partners for combination therapies. Here, we report the identification and characterization… (More)

Detection of Plasmodium falciparum male and female gametocytes and determination of parasite sex ratio in human endemic populations by novel, cheap and robust RTqPCR assays

• Federica Santolamazza, Pamela Avellino, +6 authors Valentina Dianora Mangano
• Malaria Journal
• 2017

The presence of Plasmodium falciparum gametocytes in peripheral blood is essential for human to mosquito parasite transmission. The detection of submicroscopic infections with gametocytes and the… (More)

Regression of systemic lupus erythematosus after development of an acquired toll-like receptor signaling defect and antibody deficiency.

• Marcella Visentini, Valentina Conti, +6 authors Isabella Quinti
• Arthritis and rheumatism
• 2009

Toll-like receptor 9 (TLR-9) and TLR-7 may have a role in the production of anti-DNA and anti-RNA autoantibodies, respectively, but murine models do not clearly demonstrate their contribution to the… (More)

Enlightening the malaria parasite life cycle: bioluminescent Plasmodium in fundamental and applied research

• Giulia Siciliano, Pietro Alano
• Front. Microbiol.
• 2015

The unicellular protozoan parasites of the genus Plasmodium impose on human health worldwide the enormous burden of malaria. The possibility to genetically modify several species of malaria parasites… (More)

• ‹
• 1
• 2
• ›