Giulia De Angelis

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Infections due to antibiotic-resistant Gram-negative bacteria unquestionably have substantial effects on morbidity and mortality. However, quantifying the exact economic burden attributable to these infections still remains a challenging issue. The review of the literature on this subject shows that severe infections from Gram-negative bacteria are(More)
Highest xanthone contents were found in Hypericum pulchrum and H. annulatum untransformed roots. The best anti- Candida activity was obtained for hairy roots extracts of H. tetrapterum clone 2 ATCC 15834. Extracts of root cultures, hairy roots and cell suspensions of selected Hypericum spp. were screened for the presence of xanthones and tested for their(More)
Enterobacteriaceae Determined Using Multistate Modeling at a Swiss University Hospital and a Nationwide Predictive Model Author(s): Andrew Stewardson, MBBS; Carolina Fankhauser, MS; Giulia De Angelis, MD; Peter Rohner, PhD; Edith Safran, MD; Jacques Schrenzel, MD; Didier Pittet, MD; Stephan Harbarth, MD Reviewed work(s): Source: Infection Control and(More)
Acetic acid acts as a signal molecule, strongly enhancing xanthone biosynthesis in Hypericum perforatum root cultures. This activity is specific, as demonstrated by the comparison with other short-chain monocarboxylic acids. We have recently demonstrated that Hypericum perforatum root cultures constitutively produce xanthones at higher levels than the root(More)
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