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The first results are presented of the newly established Netherlands Cancer Registry, which covers the whole Dutch population (approximately 15 million people). The registry receives data on incident cancer cases from nine autonomous regional cancer registries. Notification occurs primarily through the national registry of all pathology and haematology(More)
BACKGROUND An excessive increase in the incidence of primary central nervous system lymphoma (PCNSL) has been reported since the mid-1980s in the U.S. and U.K. Clinical studies have shown that radiotherapy and chemotherapy may prolong survival. In the current study, the authors describe the incidence, treatment, and survival of an unselected group of(More)
PURPOSE Validity and reproducibility of the Jamar dynamometer were evaluated in children aged 4-11 years. METHOD Hand grip strength was measured on the dominant side and non-dominant side in 67 patients who had been referred to our specialist centre in the past 3 years because of suspected myopathy. All the patients had had muscle biopsy. Sixteen out of(More)
In the framework of EUROCARE, a concerted action between 45 population-based cancer registries, in 17 European countries, survival of patients with primary malignant brain tumours was investigated. Survival analysis was carried out on 16,268 patients diagnosed between 1985 and 1989 and followed-up for at least 5 years. The mean European age-standardised(More)
Comparability of population-based measures of risk and prognosis for primary central nervous system (CNS) tumors, which exhibit marked histological diversity, may be hampered by differences in detection and case ascertainment and by the lack of unequivocal and uniform histological criteria for pathological diagnoses. Furthermore, many cancer registries do(More)
About 2,000 patients with primary CNS cancers, as defined by the ICD-O, were registered in four adjacent cancer registries in South and East Netherlands in 1989-1994, covering a population of more than 5 million people. About 85% of the patients were registered through pathological laboratories, concentrated in four centers for neurosurgery. Patients with a(More)
AIM To establish which instrument is the most valid and reliable measure of muscle strength in children aged 4-11 years and can improve the diagnostic procedure in children with suspected myopathy to spare more of them from muscle biopsy. METHODS In a prospective study over a 2 year period, 22 patients aged 4-11 years were recruited. They had all been(More)
OBJECTIVE To evaluate validity and reproducibility of hand-held dynamometry in 11 different muscle groups in children. DESIGN AND PATIENTS Maximum isometric muscle strength was measured with a calibrated hand-held dynamometer in 61 patients aged 4-11 years who had been referred to our specialist centre in the past 3 years because of suspected myopathy.(More)
OBJECTIVES Substantial increases in incidence and mortality rates for primary brain tumors have been reported in many, but not all, countries over the past several decades. We analyzed incidence rates for (potential) primary malignant central nervous system (CNS) tumors in an area (southeastern Netherlands) and during a period (1980-94) in which access to(More)
The authors conducted an assessment study of newly developed motor performance items for the diagnosis of myopathy. 17 children who had had muscle biopsy for this diagnosis in the recent past were administered 14 items based on the measurement of static, dynamic and explosive muscle strength and muscle endurance. Individual items did not have perfect(More)