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Changes in the airway microbiome may be important in the pathophysiology of chronic lung disease in patients with cystic fibrosis. However, little is known about the microbiome in early cystic fibrosis lung disease and the relationship between the microbiomes from different niches in the upper and lower airways. Therefore, in this cross-sectional study, we… (More)
Anaerobic bacteria have been identified in abundance in the airways of cystic fibrosis (CF) subjects. The impact their presence and abundance has on lung function and inflammation is unclear. The aim of this study was to investigate the relationship between the colony count of aerobic and anaerobic bacteria, lung clearance index (LCI), spirometry and… (More)
This article reviews disturbances in posture and gait in patients with neurological, orthopaedic and rheumatological disorders. The clinical symptoms of gait disturbances associated with upper and lower motor neuron dysfunction, extrapyramidal disorders, sensory, cerebellar and other neurological conditions as well as diseases of the skeleton are described.