Gisela Szabo

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Circadian clocks regulate daily fluctuations of many physiological and behavioral aspects in life. They are synchronized with the environment via light or temperature cycles [1]. Natural fluctuations of the day length (photoperiod) and temperature necessitate a daily reset of the circadian clock on the molecular level. In Drosophila, the blue-light(More)
Circadian clock function depends on the tightly regulated exclusion or presence of clock proteins within the nucleus. A newly induced long-period timeless mutant, tim(blind), encodes a constitutively hypophosphorylated TIM protein. The mutant protein is not properly degraded by light, and tim(blind) flies show abnormal behavioral responses to light pulses.(More)
The expression of type II classic cadherins described so far displays a wide range of partially overlapping patterns during mammalian central nervous system development indicating their potential role during migratory and lamination processes as well as axon guidance. Expression of a few members of this family however, has not been characterized in detail.(More)
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