Gisela Schön

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Acinetobacter type strains and isolates from wastewater treatment plants were differentiated by PCR fingerprinting. On the first level, PCR fingerprinting with two tRNA-gene specific primers (T5B and T3A) was used for the identification of species (genospecies 1 to 17). On the second level, a single arbitrary primer (DAF 4) was employed for strain(More)
Polyphosphate-accumulating gram-negative bacteria were isolated from different anaerobic-aerobic activated sludge systems with diverse processes for enhanced biological phosphorus (P) elimination. Of 22 isolates, 10 were allocated to the genus Acinetobacter by using multiple-test systems and soluble protein and polyamine patterns. As diaminopropane (DAP)(More)
The analysis of complex microbiota present in activated sludge is important for the understanding and possible control of severe separation problems in sewage treatment such as sludge bulking or sludge foaming. Previous studies have shown that nocardioform actinomycetes are responsible for these conditions, which not only affect the efficiency of sewage(More)
The diagnosis of Mycobacterium tuberculois (MT) using conventional microbiological methods is still a time-consuming process which, particuarly in regard to the rise of cases of drug-resistant mycobacteria, needs to be shortened. PCR is a suitable method, because of its independence of the growth of the organism. The aim of this study was to develop a PCR(More)
Wegener's granulomatosis (WG) is a rare disease characterized by granulomatous lesions, small vessel vasculitis and the presence of anti-neutrophil cytoplasmic autoantibodies (C-ANCAs) in the sera of affected patients. Their main target antigen is proteinase 3 (PR3), a neutrophil and monocyte-derived neutral serine protease. Since the standard treatment of(More)
Hitherto, few environmental samples have been investigated by a 'full cycle rRNA analysis'. Here the results of in situ hybridization experiments with specific rRNA-targeted oligonucleotide probes developed on the basis of new sequences derived from a previously described comparative 16S rRNA analysis of nocardioform actinomycetes in activated sludge are(More)
The goal of targeted immunotherapy in cancer is to damage both malignant and tumor-supporting cells of the microenvironment but spare unaffected tissue. The malignant cells in classical Hodgkin lymphoma (cHL) selectively express CD30. They release this receptor on extracellular vesicles (EVs) for the tumor-supporting communication with CD30 ligand(More)
"Institut fiir Medizinische Mikrobiologie und Hygiene, Klinikum der Albert-Ludwigs-Universitiit, Hermann-Herder-Str. 1 I, D79104 Freiburg (Germany) b Institut fiir Biologie H / M ikr ob iologie der Albert-LudwigsUniversitiit, Schiinzlestr. I, D79104 Freiburg (Germany) ~'Institut fiir Mikrobiologie und Hygiene, Universitiitsklinikum Charitb,(More)