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BACKGROUND To investigate microstructure of white matter fiber tracts in pediatric bipolar disorder (PBD) and attention-deficit/hyperactivity disorder (ADHD). METHODS A diffusion tensor imaging (DTI) study was conducted at 3 Tesla on age- and IQ-matched children and adolescents with PBD (n = 13), ADHD (n = 13), and healthy control subjects (HC) (n = 15).(More)
PURPOSE To theoretically develop and experimentally validate a formulism based on a fractional order calculus (FC) diffusion model to characterize anomalous diffusion in brain tissues measured with a twice-refocused spin-echo (TRSE) pulse sequence. MATERIALS AND METHODS The FC diffusion model is the fractional order generalization of the Bloch-Torrey(More)
The problem of optimally locating web servers across the Internet is considered. Assuming that the user demand forecast is known, the objective is to minimize cost, subject to satisfying performance requirements of customers (that access the web servers) in terms of throughput and latency thresholds. To solve the optimization problem, three heuristics are(More)
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