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The synthesis of a series of some novel Schiff base complexes of Cu(II), Ni(II), Co(II), Mn(II), Zn(II) with a tetradentate Schiff base has been achieved by the reaction of malonyl hydrazide with dehydroacetic acid in ethanol under refluxing condition. All the synthesized metal complexes and ligand were characterized on the basis of elemental analysis,(More)
In the present study, synthesis of a series of some novel 3-(Quinolin-3-yl)-5,7-dimethyl-1,2,4-triazolo[4,3-a]pyrimidine derivatives (4a–e) has been achieved by oxidative cyclization of new pyrimidinyl hydrazone intermediates (3a–e) using hypervalent iodine reagent(III) under mild conditions. The structures of all synthesized compounds were established on(More)
MicroRNAs (miRNAs) are small regulatory RNAs that play a defining role in post-transcriptional gene silencing of eukaryotes by either mRNA cleavage or translational inhibition. Plant miRNAs have been implicated in innumerable growth and developmental processes that extend beyond their ability to respond to biotic and abiotic stresses. Active in an(More)
In recent years, soybean [Glycine max (L.) Merrill] has emerged as a major rainy season cash crop in central India. In the present study, the changes in soybean scenario over a period from 2001 to 2013 of Indore district and Madhya Pradesh since 1980 with respect to area sown, production, and productivity are discussed, taking in consideration the changes(More)
In search of a new class of organic compounds as potential COX-2 inhibitors, various 4-Fluorophenylhydrazones (3a–3i) have been synthesized and molecular docking study was conducted. All the synthesized compounds were also evaluated for their in vivo anti-inflammatory potential using carrageenan-induced rat paw odema method. In the present manuscript, a(More)
In search of a new class of potential antimicrobial agents, some 1,4-diaryl-2-mercaptoimidazoles (5a–5h) were prepared by employing a mild and green approach in which substituted anilines 3 were treated with phenacylbromide 2 in the presence of Na2CO3/K2CO3 followed by the treatment of a solid catalyst, p-TSA (para toluene sulphonic acid), to give imidazole(More)
Objective Eukaryotic cilia/flagella are dynamic microtubule (MT)-based organelles. The ciliary axoneme is built from a radial scaffold of 9 MT doublets, plus a central MT pair, in the case of motile cilia. The axoneme is templated by a basal body (BB)/centriole derived from the mother centriole, in the case of animal cells, which presents sub-distal and(More)