Giri Prasad Joshi

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Common wheat (Triticum aestivum L.) is one of the most important cereals in the world. To improve wheat quality and productivity, the genomic sequence of wheat must be determined. The large genome size (∼17 Gb/1 C) and the hexaploid status of wheat have hampered the genome sequencing of wheat. However, flow sorting of individual chromosomes has allowed us(More)
Rapid proliferation in small cell lung cancer (SCLC) may be mediated by synthesis of autocrine growth factors. Bombesin (or its mammalian homologue gastrin releasing peptide, GRP) may have autocrine function in SCLC (Cuttitta et al., 1985; Carney et al., 1987) but is not synthesised by the faster growing variant SCLC lines (Carney et al., 1985).(More)
SCLC cell lines exhibit considerable heterogeneity as regards morphology, biochemistry and growth kinetics (Carney et al., 1985a). 'Classic' SCLC lines commonly grow as floating aggregates (morphology type I or II) and possess neuro-secretory granules (NSG) on electron microscopy. They express four biomarkers: creatine kinase-BB (CK-BB), neurone specific(More)
Gametocidal (Gc) chromosomes induce various types of chromosomal mutations during gametogenesis in the chromosomes of common wheat and alien chromosomes added to common wheat. However, it is not yet known whether the Gc chromosome causes aberrations at the nucleotide level because mutations caused by Gc chromosomes have been studied only by cytological(More)
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