Giovanni Rotondo

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2 Research Division, Joslin Diabetes Center, Boston, Massachusetts, 3 Department of Medicine, Harvard Medical School, Boston, Massachusetts; 4 Department of Experimental Medicine, Sapienza University, Rome, Italy; 5 IRCSS Casa Sollievo della Sofferenza, Department of Medicine, San Giovanni Rotondo, Italy; 6 IRCSS Casa Sollievo della Sofferenza, Research(More)
The conventional criterion for fracture risk assessment is the bone mineral density (BMD) measured by X-ray absorptiometry. Even if there is a strong association between bone strength and BMD, nowadays it is well accepted that this is not a sufficiently reliable predictor of fracture risk in osteoporotic patients. Therefore, there is a growing need for a(More)
Isolated tetralogy of Fallot (TF) has a multifactorial mode of inheritance in most cases, and recurrence risk rates of 2.5-3% have been attributed to first degree relatives of an affected child. In a subgroup ofpatients with a strong family history, the transmission of a monogenic trait has been suspected. Microdeletion 22qll (del(22ql1)) can cause TF in(More)
In light of the modern aetiopathogenic views, a brief review was made concerning possible causes of operational fatigue to which flying personnel in general are exposed in the exercise of flying activity. The author then describes and analyzes the meaning and importance of the various stressing factors that constitute the physical and psychic workload to(More)