Giovanni Leuzzi

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OBJECTIVES Thymectomy plays an important role in patients with myasthenia gravis (MG). This study aimed to explore predictors of postoperative myasthenic crisis (POMC) after thymectomy and to define a predictive score of respiratory failure. METHODS The clinical data of 177 patients with MG undergoing thymectomy from January 1995 to December 2011 were(More)
A 43-year-old white male was referred to the Emergency Department with acute onset of severe dyspnea, cyanosis, and dry cough. He previously underwent a left-foot amputation in 2011 for synovial-sarcoma. In 2012, the patient experienced a relapse with bilateral lung metastases (Fig 1) and, two months before admission, he started Pazopanib (Votrient, Glaxo(More)
BACKGROUND Despite ongoing efforts to improve therapy in malignant pleural mesothelioma, few patients undergoing extrapleural pneumonectomy experience long-term survival (LTS). This study aims to explore predictors of LTS after extrapleural pneumonectomy and to define a prognostic score. METHODS From January 2000 to December 2010, we retrospectively(More)
BACKGROUND To address the question of how much chest-wall (CW) resections and prosthetic reconstructions influence functional outcome. METHODS We retrospectively reviewed 175 patients who underwent surgery for CW tumors. The clinical, histological, surgical, oncological, and functional factors were analyzed. RESULTS We performed: 75 rib resections; 20(More)
PURPOSE The prognostic impact of baseline C-reactive protein (CRP) in non-small-cell lung cancer (NSCLC) is debated. To evaluate this issue, we performed a systematic review and meta-analysis to explore the role of CRP value in predicting early-stage NSCLC survival. METHODS Ten articles on early-stage NSCLC were eligible and included in our study. We(More)
OBJECTIVES The efficacy of endoscopic ultrasound (EUS) for evaluating mediastinal adenopathy in lung cancer is nowadays proven. However, its accuracy for detection of malignant pleural effusion per se has not been yet investigated. Herein we report our experience with EUS for detecting pleural effusion during the staging procedure of non-small cell lung(More)
Zuin et al. [1] have recently reported an interesting retrospective analysis on a relative large series of second primary non-small-cell lung cancers (NSCLCs), comparing the long-term outcomes between patients treated with a lobectomy and those where a sub-lobar resection was performed, which prompted a series of reflections by us, discussed here. The best(More)