Giovanni Foresti

Learn More
OBJECTIVE The purpose of this study was to describe the clinical characteristics and related comorbid conditions of psychiatric patients admitted to residential facilities (RFs) and their impact on the levels of functioning of such patients. METHODS We assessed 426 patients admitted to residential facilities, by using SCID-I, SCID-II, BPRS, GAF and DAS.(More)
Reactive oxygen species (ROS) have been suggested to play an important role in physiopathology of schizophrenia. The polymorphisms in the genes encoding antioxidant enzymes, such as manganese superoxide dismutase (MnSOD) should, thus, result in predisposition to this psychiatric disorder. A functional amino acid polymorphism (Ala9Val) has been described in(More)
We report on a 5p- azoospermic male not showing the clinical features diagnostic for the cri-du-chat syndrome but for a breathy, raspy voice. The 5p deletion breakpoint, determined by fluorescent in situ hybridization (FISH) analysis with BAC clones, maps 8.5 Mb far from the short arm telomere in 5p15.31. Genotype/phenotype correlations in this subject,(More)
A process of protein aggregation that causes intracellular or extracellular accumulation of insoluble protein deposits causes many important neurodegenerative diseases associated with the ageing. The recognition that protein aggregation plays a prominent role in pathogenesis of important pathologies such as Alzheimer's and Parkinson's diseases prompted the(More)
The first draft of the fifth version of the American Diagnostic and Statistical Manual (DSM-V) provides an opportunity to clarify the several issues associated with the debate on diagnostic process in psychiatry. Several peculiar aspects of the DSM approach showed stability over time suggesting that this project is rooted in an original conception of mental(More)
A survey of 55 old people's homes in Liguria, a region in northern Italy, was carried out to investigate some social and demographic characteristics of the residents, their level of dependence and management. A total of 1666 residents was randomly selected and information was obtained from the records and from an interview with the care staff. Homes(More)
The identification of the molecular basis of numerous hereditary neurological disorders allowed the feasibility of predictive genetic tests for at-risk family members. In agreement with international guidelines, we tested a protocol for a predictive test to optimize cooperation among specialists, well-being of participants, and organization of clinical(More)
The Organic Brain Syndrome (OBS) and the Depression (D) scales derived from the Comprehensive Assessment and Referral Evaluation (CARE) were translated into Italian and used in a survey of geriatric institutions in Milan. During the survey validity and reliability tests of the scales were conducted. Inter-rater reliability (total score weighted kappa) was(More)
Five specific personality traits (emotivity, acceptance of sexual role, parental aptness, anxiety and depression) have been analyzed for this study of the premenstrual syndrome (PMS), conducted on a group of 110 women in advanced (8th month) pregnancy. The comparison of the results from the personality tests and from the overall assessment of the PMS (82%)(More)