Giovanni Chiari

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D iabetic ketoacidosis (DKA) in children with type 1 diabetes at onset is considered an increased risk factor of death and is generally related to a long duration of misdiagnosed hyperglycemia-associated symptoms (1). Shortening this latency period could be a winning preventive strategy. In the period of 1991– 1997, we investigated this hypothesis in the(More)
We conducted a retrospective survey in pediatric centers belonging to the Italian Society for Pediatric Diabetology and Endocrinology. The following data were collected for all new-onset diabetes patients aged 0-18 years: DKA (pH < 7.30), severe DKA (pH < 7.1), DKA in preschool children, DKA treatment according to ISPAD protocol, type of rehydrating(More)
In this paper the preliminary findings of a multicentre study on the effects of Acetyl-L-Carnitine on mildly impaired elderly are reported. Statistical analysis was carried out on 236 out of 469 subjects sampled in 42 different Italian geriatric or hospital units. Each subject was treated over 150 days, and a battery of tests (investigating cognitive(More)
T he prevalence of eating disorders and behaviors was evaluated in two populations of adolescents with type 1 diabetes from two cities in Italy. In this report, we will establish the relationship of these disorders with sex, BMI, socioeconomic status, metabolic control, and compliance to therapy. A total of 193 patients with type 1 diabetes aged 8 –18 years(More)
This longitudinal population-based study analyses the frequency of diabetic ketoacidosis (DKA) at type 1 diabetes diagnosis in Italian children under 15 years of age, during 2004-2013. DKA was defined as absent (pH ≥ 7.30), mild/moderate (7.1 ≤ pH < 7.30) and severe (pH < 7.1). Two multiple logistic regression models were used to evaluate the time trend of(More)
The knowledge about the long-term consequences of diabetes with onset in the neonatal period is scanty. We investigated the impact of long-standing diabetes (.15 years) on the retina of 10 patients with permanent neonatal diabetes mellitus (PNDM) (diabetes diagnosis within 6 months of birth) associated with mutations of GCK, KCNJ11, INS, or ABCC8 genes and(More)
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