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Journals and Conferences
A quantitative EEG analysis was performed on the posterior lead of 18 patients with their eyes closed 3-10 days after minor head injury. There was a significant increase of the mean power of slow alpha (8-10 c/sec), a reduction of fast alpha (10.5-13.5 c/sec), with a shift of mean alpha frequency towards lower values, and a reduction of fast beta (20.5-36… (More)
Herbal preparations have been used for centuries as the main therapeutic means. In Italy there is an ancient tradition of using herbal remedies, which became extremely important from the 16th to the 18th century. Nowadays multinational companies invest great resources on herbal drugs and preparations. This article focuses on herbal medicines, herbal… (More)
From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, pilosidine, previously obtained only as the tetra-O-methyl derivative, were isolated. Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
The Curculigo pilosa total extract, its butanolic fraction (0.5 microg-100 mg/kg) and the most active in vitro compound structurally similar to adrenaline, pilosidine (10 ng-l mg/kg), caused a reversible and dose-dependent increase in blood pressure in anaesthetized rat. This hypertensive effect is partially reversed (90%) by the prior administration of… (More)
Equisetum arvense L. is a herbaceous medicinal plant, commonly known as horsetail, whose extracts have been reported to possess diuretic and haemostatic properties. The aim of this study was to evaluate the use of fingerprint chromatographic methods on commercially available raw materials or preparations of E. arvense L. in order to ascertain their quality… (More)
The in vivo antiplasmodial activity of voacamine was assessed in a 4-day test. It was shown to exhibit in vivo activity with 25.4% and 43.4% inhibition of parasitaemia with 2.5 and 10 mg/kg, respectively. In synchronized cultures, it was found to act on trophozoite and schizont stages of Plasmodium falciparum. Using the FMC29 strain of Plasmodium falciparum… (More)
Phymatodes scolopendria (Burm.) Ching (Polypodiaceae) is widely used in the Eastern coast of Madagascar to treat respiratory disorders. Bioassay-guided fractionation using guinea pig trachea pre-contracted with histamine to monitor the activity led to the isolation of 1,2-benzopyrone (coumarin) as the main active constituent. Effectively, it induced a… (More)
The tertiary and quaternary alkaloids isolated from the stem bark, root bark and seeds of Peschiera fuchsiaefolia are reported. The tertiary alkaloid crude extract from the stem bark was tested in vitro against Plasmodium falciparum on the basis of the antimalarial use of the plant. It showed good activity against both the D6 strain (IC50 = 495 ng/ml) and… (More)
In Italy most herbal products are sold as food supplements and are subject only to food law. A list of about 1200 plants authorised for use in food supplements has been compiled by the Italian Ministry of Health. In order to review and possibly improve the Ministry's list an ad hoc working group of Istituto Superiore di Sanità was requested to provide a… (More)
The isolation, (13)C-NMR and CD data of two 7-epimer oxindole alkaloids, 10,11-dimethoxyisomitraphylline (1) and 10,11-dimethoxymitraphylline (2) from Cabucala cryptophlebia are reported.