Giorgio Russo

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BACKGROUND A new transcranial focused ultrasound device has been developed that can induce hyperthermia in a large tissue volume. The purpose of this work is to investigate theoretically how glioblastoma multiforme (GBM) can be effectively treated by combining the fast hyperthermia generated by this focused ultrasound device with external beam radiotherapy.(More)
BACKGROUND In this paper the clinical value of PET for early prediction of tumor response to erlotinib in patients with advanced or metastatic non-small cell lung cancer (NSCLC) after failure of at least one prior chemotherapy regimen is evaluated. The aim was to compare the early metabolic treatment response using European Organization for Research and(More)
Radiotherapy techniques permit to deliver ionizing radiations (X-rays, photons, electrons, protons, etc) inside cancerous tissues to kill the abnormal-cells. Radiotherapy related activities, as the optimization of the therapeutic radiation dose to the patient, worker radioprotection, performance controls and technical innovations of linear accelerators, are(More)
A small number of studies evaluated the detection rate of lesions from bladder carcinoma (BC) of 18 F-FDG PET/CT in the restaging process. However, the prognostic role of FDG PET/CT still remains unclear. The aim of the present study was to evaluate the accuracy, the effect upon treatment decision, and the prognostic value of FDG PET/CT in patients with(More)
Uterine fibroids are benign tumors that can affect female patients during reproductive years. Magnetic resonance-guided focused ultrasound (MRgFUS) represents a noninvasive approach that uses thermal ablation principles to treat symptomatic fibroids. During traditional treatment planning, uterus, fibroids, and surrounding organs at risk must be manually(More)
Fibroids are benign tumors growing in the uterus. Most of fibroids do not require treatment unless they are causing symptoms. Traditional surgery treatments, like myomectomy and hysterectomy, are very invasive therapeutic approaches which not always preserves reproductive potential of the woman. MRgFUS, performed with Insightec ExAblate 2100 equipment, is a(More)
Target volume delineation of Positron Emission Tomography (PET) images in radiation treatment planning is challenging because of the low spatial resolution and high noise level in PET data. The aim of this work is the development of an accurate and fast method for semi-automatic segmentation of metabolic regions on PET images. For this purpose, an algorithm(More)
OBJECTIVE To assess the predictive and prognostic value of progressive metabolic disease (PMD) by the use of early 18Fluorodeoxyglucose positron emission tomography (18FDG-PET) in patients with clinical stage IV non-small cell lung cancer (NSCLC) treated with first-line chemotherapy. METHODS An 18FDG-PET performed following the first cycle of chemotherapy(More)
Vladimir IVANCHENKO, John APOSTOLAKIS, Alexander BAGULYA, Haifa Ben ABDELOUAHED, Rachel BLACK, Alexey BOGDANOV, Helmut BURKHARD, Stéphane CHAUVIE, Pablo CIRRONE, Giacomo CUTTONE, Gerardo DEPAOLA, Francesco Di ROSA, Sabine ELLES, Ziad FRANCIS, Vladimir GRICHINE, Peter GUMPLINGER, Paul GUEYE, Sebastien INCERTI, Anton IVANCHENKO, Jean JACQUEMIER, Anton(More)
BACKGROUND Intraoperative electron radiation therapy (IOERT) is a therapeutic technique which administers a single high dose of ionizing radiation immediately after surgical tumor removal. IOERT induces a strong stress response: both tumor and normal cells activating pro- and antiproliferative cell signaling pathways. Following treatment, several genes and(More)