Gino Di Domenico

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The Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a hematopoietic growth factor that regulates the in vitro and in vivo proliferation and differentiation of hematopoietic cells through the interaction with a specific heterodimeric receptor complex (GM-CSFR), consisting of an a and a b chain with molecular weights of 80 and 120 KDa,(More)
The effect of different training intensities of electro-motor stimulation (EMS) on strength gains produced in the quadriceps femoris muscle group was investigated. Twenty-four subjects were randomly assigned to one of three groups: Control (C), Low Intensity (LI) trained at 25% of their maximum voluntary isometric contraction (MVIC), and High Intensity (HI)(More)
A prototype for Positron Emission Mammography, the YAP-PEM, is under development within a collaboration of the Italian Universities of Pisa, Ferrara, and Bologna. The aim is to detect breast lesions, with dimensions of 5mm in diameter, and with a specific activity ratio of 10:1 between the cancer and breast tissue. The YAP-PEM is composed of two stationary(More)
The capability of the scintimammography to diagnose subcentimeters sized tumors was increased by the employment of a dedicated gamma camera. The introduction of small field of view camera, based on pixellated scintillation array and position sensitive photomultiplier, allowed to enhance the geometric spatial resolution and contrast of the images due to(More)
Telomeres are specialized nucleoprotein structures that have two important functions: (i) protection of the chromosomal ends from deleterious events such as chromosome fusion and degradation; (ii) counteraction of the “end replication problem” by allowing telomerase-dependent or, more rarely, telomerase-independent telomere elongation. The DNA sequences(More)
The effect of different training intensities on maximum voluntary isometric contraction (MVIC) strength was examined in a three week voluntary isometric exercise programme. Eighteen healthy university students were randomly assigned to one of three training groups: Low Intensity (LI), High Intensity (HI) and Maximal Effort (ME) groups. The LI and HI groups(More)
In this article we report on the use of degenerate-Raman-sideband cooling for the collimation of a continuous beam of cold cesium atoms in a fountain geometry. Thanks to this powerful cooling technique we have reduced the atomic beam transverse temperature from 60 mK to 1.6 mK in a few milliseconds. The longitudinal temperature of 80 mK is not modified. The(More)
A prototype of a combined CT–SPECT tomograph for breast cancer study has been developed and evaluated. It allows to perform scintimammography and X-ray CT in the same geometrical conditions. The CT system is based on a quasi-monochromatic beam tuned at 28 keV and an array of ultra fast ceramic scintillators coupled to photodiodes whilst the SPECT system is(More)
An ideal direct imaging system entails a method to illuminate on command a single diffraction-limited region in a generally thick and turbid volume. The best approximation to this is the use of large-aperture lenses that focus light into a spot. This strategy fails for regions that are embedded deep into the sample, where diffraction and scattering prevail.(More)