Gino C. Catena

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Congenital cytomegalovirus (CMV) is frequently associated with active retinitis. In contrast, in the immunocompetent neonate with postnatally acquired CMV infection retinitis is rarely present and usually does not progress. We describe the case of an infant with postnatal CMV infection and active retinitis diagnosed at 20 days of life. Owing to the rapid(More)
Thermodynamic parameters and stoichiometries for the binding of anilinonaphthalenesulfonates to beta-cyclodextrin are obtained from steady-state fluorescence intensity and anisotropy measurements. Specifically, formation constant, enthalpy, and entropy values are obtained for complexes of beta-cyclodextrin with eight different substrate molecules at five(More)
BACKGROUND Despite the optimization of neonatal assistance, severe retinopathy of prematurity (ROP, stage III-IV) remains a common condition among preterm infants. Laser photocoagulation usually requires general anesthesia and intubation, but extubation can be difficult and these infants often affected by chronic lung disease. We retrospectively evaluated(More)
The results of four diagnostic tests have been critically evaluated (xylosemia, serum Ig A level, steatorrhea, X-Ray of the digestic tract) in 80 cases of atrophy of the small intestinal mucosa discovered by biopsy, and in 20 cases in which the biopsy has proved normal. In the celiac subjects the best correlation with the biopsy was found with xylosemia(More)
To describe the morphofunctional findings in a 6-year-old child with a unilateral lesion of the temporal macula called “torpedo maculopathy” throughout a 1-year follow-up. Evaluation of retinal morphology and function was assessed by means of spectral-domain OCT scans, best-corrected visual acuity, full-field flash electroretinogram (ERG), multifocal(More)
Familial exudative vitreoretinopathy (FEVR) is a complex disorder characterized by incomplete development of the retinal vasculature. Here, we report the results obtained on the spectrum of genetic variations and correlated phenotypes found in a cohort of Italian FEVR patients. Eight probands (age range 7-19 years) were assessed by genetic analysis and(More)
We describe the case of an infant with a retinitis due to a postnatally acquired Cytomegalovirus, successfully treated at six months of life with three cycles of intravitreal injections of pegaptanib sodium. The therapy was effective in modulating the retinal disease activity in this immunocompetent child, without any side effect observed at a long-term(More)
Fluorescence lifetimes are reported for a series of anilinonaphthalene sulfonate (ANS) probe molecules complexed with β-cyclodextrin (β-CD). The fluorescence decay kinetics are recovered by multifrequency phase and modulation measurements in concert with a global analysis scheme. In all cases studied, a continuous Lorentzian distribution of lifetimes is(More)
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