Learn More
OBJECTIVE To determine the risk of major birth defects in cohorts of children conceived through IVF or through IUI as compared with naturally conceived children. DESIGN Retrospective cohort study. SETTING Academic medical center. PATIENT(S) Children conceived by IVF or IUI at the University of Iowa from 1989 through 2002, compared with a matched(More)
OBJECTIVE To determine the proportion of infertile women who prefer a multiple birth over a singleton, patient characteristics associated with this desire, and patient knowledge about the risks of multiple births. DESIGN Prospective analysis. SETTING Academic university hospital-based infertility center and private general gynecology clinic. (More)
OBJECTIVE To reduce the twin rate in our IVF program. DESIGN A prospective educational study of infertile couples; a retrospective review of IVF outcomes before vs. after mandatory single embryo transfer (mSBT) policy change. SETTING University-based infertility center. PATIENT(S) One hundred ten of 120 consecutive new infertile couples completed the(More)
OBJECTIVE To report the outcomes of a program policy instituted in 2004 mandating single-embryo transfer (mSET) for all women aged <38 years, with at least seven zygotes, no prior failed fresh cycle at our center, and at least one good-quality blastocyst. DESIGN Retrospective cohort study. SETTING Academic medical center. PATIENT(S) All women <38(More)
While depression has been associated with infertility treatments, it is not routinely assessed in women prior to undergoing in vitro fertilization (IVF) treatment. Findings are mixed regarding the degree to which women report depression prior to IVF. The purpose of this study was to (1) examine response profiles in women preparing for IVF and (2) compare(More)
STUDY OBJECTIVE To compare sexual attitudes and behaviors of young women who have received or declined the HPV vaccine. DESIGN Cross-sectional survey. SETTING Obstetrics and gynecology and pediatrics clinics at a large, Midwestern, academic health center. PARTICIPANTS 223 young women (ages 13-24): 153 who had received HPV vaccination and 70 with no(More)
OBJECTIVE To determine the clinical factors associated with blastocyst development and pregnancy. DESIGN Evaluation of a prospectively collected IVF database. SETTING An academic IVF practice. PATIENT(S) Couples (n = 529) undergoing their first IVF cycle who qualified for extended embryo culture (more than six zygotes) over the past 5 years. (More)
OBJECTIVE To investigate the role of mutations or polymorphisms in the NPY-Y1R gene in human idiopathic central pubertal disorders. DESIGN Molecular studies. SETTING University hospital. PATIENT(S) Thirty-three patients with gonadotropin-dependent precocious puberty, 22 with hypogonadotropic hypogonadism, and 50 controls. INTERVENTION(S) Genomic DNA(More)
OBJECTIVE To describe a unique vaginal outlet obstruction and its ultrasound-assisted surgical correction. DESIGN Case report. SETTING An academic medical center. PATIENT(S) A 12-year-old girl was seen with cyclic abdominal pain, nausea, and an abdominal mass. External genital examination revealed no vaginal opening or dimple. Transabdominal(More)