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PermutMatrix is a work space designed to graphically explore gene expression data. It relies on the graphical approach introduced by Eisen and also offers several methods for the optimal reorganization of rows and columns of a numerical dataset. For example, several methods are proposed for optimal reorganization of the leaves of a hierarchical clustering(More)
BACKGROUND High-throughput sequencing technologies offer new perspectives for biomedical, agronomical and evolutionary research. Promising progresses now concern the application of these technologies to large-scale studies of genetic variation. Such studies require the genotyping of high numbers of samples. This is theoretically possible using 454(More)
Two-dimensional gel electrophoresis, a routine application in proteomics, separates proteins according to their molecular mass (M(r)) and isoelectric point (pI). As the genomic sequences for more and more organisms are determined, the M(r) and pI of all their proteins can be estimated computationally. The examination of several of these theoretical proteome(More)
We have developed a specialised proteomic database for the analysis of matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) data derived from tryptic peptides of Sinorhizobium meliloti proteins. This database currently contains the amino acid sequence data of the proteins predicted from the complete chromosome,(More)
We propose a novel BIST technique for non-scan sequential circuits which does not modify the circuit under test. It uses a learning algorithm to build a hardware test sequence generator capable of reproducing the essential features of a set of precomputed deterministic test sequences. We use for this purpose two new models called Hidden Markov Model with(More)