Gilda A. Barabino

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While the percentage of women in biomedical engineering is higher than in many other technical fields, it is far from being in proportion to the US population. The decrease in the proportion of women and underrepresented minorities in biomedical engineering from the bachelors to the masters to the doctoral levels is evidence of a still leaky pipeline in our(More)
The pathophysiology of vaso-occlusive crisis in sickle cell disease involves interactions among blood cells, plasma proteins, and vessel wall components. The initial goal of this work was to quantify the adhesion of sickle red blood cells (RBCs) to fibronectin immobilized on glass under both static and dynamic shear stress conditions. High-power microscopic(More)
BACKGROUND Mesenchymal stem cells (MSCs) are viewed as a having significant potential for tissue engineering and regenerative medicine therapies. Clinical implementation of MSCs, however, demands that their preparation be stable and reproducible. Given that environmental and bioprocessing parameters such as substrate stiffness, seeding densities, culture(More)
Successful integration of engineered constructs with host tissues is crucial for cartilage repair, yet achieving it remains challenging. A collagen I-based fibrous capsule characterized by increased cell density and decreased glycosaminoglycan deposition usually forms at the periphery of tissue-engineered cartilage. The current study aimed to evaluate the(More)
In this first of a series of Biomedical Engineering Society (BMES) presidential editorials, my intent is to share my vision for the Society and encourage the full engagement of its membership as stewards of the profession, to ensure the continued success of BMES and to meet societal goals. Biomedical Engineering (BME) is the fastest growing engineering(More)
Many individuals contributed to the development and preparation of the Advisory Committee to the (NIH) Director (ACD) Long-Term Intramural Research Program (LT-IRP) planning working group (WG) report. First and foremost, we thank Drs. Michael Gottesman and Richard Wyatt for their assistance in providing much of the data that describe the National Institutes(More)
The development of tissue engineered osteochondral units has been slowed by a number of technical hurdles associated with recapitulating their heterogeneous nature ex vivo. Subsequently, numerous approaches with respect to cell sourcing, scaffolding composition, and culture media formulation have been pursued, which have led to high variability in outcomes(More)
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