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Images of mammalian organs were built up using a Laser collimated transillumination device equipped with a bidirectional scanning setup. A microcomputer was used to run the scanning process, acquisition of detected signals and images restitution. The images featured a satisfactory resolution of optical discontinuities on both sample surfaces. Light(More)
Pain-related cortical potentials were evoked by skin stimulation of the face and the limbs with 5-ns-duration laser pulses delivered by a Q-switched Nd:YAG laser. Such laser pulses, in the nanosecond range, were able to induce pinprick pain sensations and to evoke reproducible laser evoked potentials (LEPs) without visible skin lesions for an energy density(More)
The main aim of this study was to examine the temporal aspects of neuronal changes during the observation and execution of simple and complex tasks to gain a greater understanding of the mirror neuron system’s involvement in complex motor tasks. Eleven right-handed subjects observed simple and complex finger movement sequences. Electroencephalograms were(More)
For use with intact perfused organs a spectrophotometer system has been developed, both for dual-wavelength absorption measurements and for spectral scanning. A monochromator is used for illumination and scanning in the visible and near infrared. Optic fibres conduct light to the specimen under examination and from the specimen to a detecting(More)
The aim of this study was to provide further evidence for the existence of a mirror neuron system in humans using electroencephalography during the observation and execution of non-object-related movements. Event-related desynchronization and synchronization (ERD/ERS) were used to characterize brain activity prior to, and during, observation and execution(More)
The aim of this study was to test the validity of mirror neuron activity in humans through analysis of electroencephalographic (EEG) functional connectivity during an action not directed towards an object. We investigated changes in EEG interchannel synchronization prior to and during action execution and also prior to and during observation of the same(More)
The aim of this study was to examine the effects of instructions and expertise upon neuronal changes during observation of sequential finger movements. Professional pianists and musically naïve subjects observed these movements with the aim of either replicating or recognizing them at a later stage. A non-linear measure of functional coupling was used to(More)
OBJECTIVE To assess the modulation of acute provoked pain by repetitive transcranial magnetic stimulation (rTMS) of the motor cortex in patients with chronic neuropathic pain. METHODS In 32 patients with chronic neuropathic pain affecting one upper limb, laser-evoked potentials (LEPs) (N2 and P2 components) were recorded in response to laser stimulation(More)
The clinical interest of a new type of laser evoked potentials (LEPs) using Nd:YAG laser was assessed in the diagnosis of peripheral neuropathies affecting the small-diameter nerve fibres, and of spinal cord lesions, affecting the spinothalamic tract. Twelve patients aged from 26 to 79 years with sensory neuropathies (n = 6) or spinal cord lesions (n = 6)(More)
In vivo dual wavelength differential spectrography was performed on the hand of an adult male, using a collimated transillumination device. A pulsed laser with sufficiently high peak power and sufficiently low energy was employed so that transillumination could be realized without thermal damage. Spectrochemical analysis based on the absorbance of oxygen(More)