Gil França

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Proteinuria after strenuous exercise is common in healthy subjects. The pathophysiologic mechanism of postexercise proteinuria (PEP) is not clear, although the phenomenon has long been known and many explanatory theories have been proposed. It is widely recognized that angiotensin II may increase filtration of protein through the glomerular membrane, and(More)
Angiotensin converting enzyme inhibitors have been proposed to have a prostaglandin-dependent component to their hypotensive action. The aim of this study was to assess whether the structurally dissimilar angiotensin converting enzyme inhibitors captopril and enalapril stimulate the synthesis of prostacyclin, whether their hypotensive action is blunted by(More)
The relationship between body weight excess and hypertension has been widely demonstrated. Some body-builders can reach an important body weight excess because of the skeletal muscle hypertrophy; their body mass index is comparable to that of obese subjects, although body fat excess is responsible for overweight in the latter. Blood pressure, fasting plasma(More)
Much clinical evidence supports the use of angiotensin-converting enzyme inhibitors (ACE-I) as the first-step drugs in the treatment of essential hypertension. The acute and chronic effects of ACE-I on renal function are reviewed in this paper. The kidney is an important target organ of essential hypertension and some antihypertensive drugs have been shown(More)
Many experimental evidences suggest an important role of calcium in the pathophysiology of essential hypertension; an increased calciuria could be a feature of these patients. Provocative tests, such as cold pressor test or aerobic exercise, have been proposed to be predictive for the occurrence of essential hypertension. Aim of this study has been to show(More)
Dunbar syndrome or celiac artery compression syndrome is an infrequently described clinical condition with poorly defined diagnostic criteria and an obscure pathophysiology. It is usually associated with an extrinsic compression upon the celiac axis near its takeoff from the aorta by fibrous diaphragmatic bands or sympathetic neural fibers. The authors(More)
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