Gijs H. M. van Puijvelde

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Discovery of novel biomarkers for atherosclerosis is important to aid in early diagnosis of pre-symptomatic patients at high risk of cardiovascular events. The aim of the present study was therefore to identify potential biomarkers in circulating cells reflecting atherosclerotic lesion progression in the vessel wall. We performed gene arrays on circulating(More)
It has been shown that natural killer T (NKT) cell activation accelerates atherosclerosis in apoE-/mice. ApoE is, however, an important mediator in the presentation of lipids which may complicate conclusions on the role of NKT cells in atherosclerosis. Treatment of LDLr-/mice with α-GalCer during Western-type diet feeding is therefore of interest.(More)
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