Gigliola Bedetti

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BACKGROUND Ultrasound lung comets (ULCs) are a clinically useful sign of extravascular lung water. They require very limited technology (2 D-echo), and a short learning curve. The aim of the present study is to compare ULCs information obtained by experienced echocardiologists using a full feature echocardiographic platform and by inexperienced sonographers(More)
OBJECTIVES We investigated the relationship between intima-media thickening (IMT) as an expression of preclinical atherosclerosis and coronary risk factors, including the autonomic nervous system and inflammation markers, in depressed subjects free from coronary artery disease. METHODS We studied 391 asymptomatic subjects with a cluster of risk factors,(More)
Risk stratification in patients with acute coronary syndromes (ACS) is achieved today by clinical models, "blind" to the prognostic support of imaging methods. To assess the value of simple at rest cardiac chest sonography in predicting the intra- and extrahospital risk of death or myocardial infarction, we enrolled 470 consecutive in-patients (312 men, age(More)
Medical radiation from X-rays and nuclear medicine is the largest non-natural (man-made) source of radiation exposure in Western countries. The aim of this study was to assess the individual cumulative effective dose in patients admitted to our cardiology ward. We collected a cumulative radiological history from a structured questionnaire and access to(More)
BACKGROUND Dobutamine-stress and dipyridamole-stress echocardiographies are widely used for pharmacological stress echocardiography, with wide geographical variations. OBJECTIVE To assess whether evidence derived from the literature indicates or disapproves that either stress modality confers diagnostic superiority. METHODS We performed a meta-analysis(More)
OBJECTIVE Patients undergoing radiologic and nuclear medicine examination often receive little, if any, information related to the radiologic dose and consequent potential long-term cancer risk. This "economical with the truth" communication may violate basic patients' rights. We assessed the information perceived by patients on the radiation dose exposure(More)
BACKGROUND Emergency room (ER) evaluation of patients with acute chest pain and non-diagnostic electrocardiography (ECG) remains a frequent and difficult problem. AIM To assess safety and prognostic implications of pharmacological stress echocardiography in the ER chest pain unit (CPU). METHODS A total of 552 patients (321 males, age 58+/-12.6 years)(More)
Use of radiation for medical examinations and tests is the largest manmade source of radiation exposure. No one can doubt the immense clinical and scientific benefits of imaging to the modern practice of medicine. Every radiological and nuclear medicine examination confers a definite (albeit low) long-term risk of cancer, but patients undergoing such(More)
BACKGROUND Diagnosis costs for cardiovascular disease waste a large amount of healthcare resources. The aim of the study is to evaluate the clinical and economic outcomes of alternative diagnostic strategies in low risk chest pain patients. METHODS We evaluated direct and indirect downstream costs of 6 strategies: coronary angiography (CA) after positive(More)
BACKGROUND High-dose glucose-insulin-potassium (GIK) solution has beneficial effects on reducing mortality in acute myocardial infarction. Dipyridamole (DIP) is a powerful antioxidant and increases adenosine concentration. Experimentally, GIK and DIP have additive protective effects in ischemia-reperfusion injury. AIM This work aims to assess the acute(More)