Gianni Pizzolo

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BACKGROUND Neutrophilic-chronic myeloid leukemia (CML-N) has been described as a CML variant associated both with a distinctive molecular defect of the Philadelphia chromosome and with a more benign clinical course than classic CML. The translocation (9;22) in CML-N results in the transcription of an e19/a2 type BCR/ABL mRNA that codes for a 230-kD BCR/ABL(More)
The diversity of immunoglobulin (Ig) molecules and antigen-specific receptors on lymphoid cells, the activation processes during the immune response, the clonal propagation of cells stimulated by anti-gens, and the sophisticated control mechanisms in the immune system are unparalleled in other biological systems (see A. R. Williamson at page 76, and P. C.(More)
Bivariate flow cytometric analysis of proliferating cell nuclear antigen (PCNA) was performed on prostate carcinoma cell lines (PC-3, DU-145). For both cell lines 100% methanol fixation provided optimal fluorescence intensity of PCNA. The ratio of PCNA/DNA increased in late G1 through early S/phase, followed by a decrease in mid- and late S and enhancement(More)
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