Gianluca Botto

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BACKGROUND Heart failure(HF) and atrial fibrillation(AF) frequently coexist in the same patient and are associated with increased mortality and frequent hospitalizations. As the concomitance of AF and HF is often associated with a poor prognosis, the prompt treatment of AF in HF patients may significantly improve outcome. METHODS/DESIGN Recent implantable(More)
— The research community is devoting increasing attention to software routers based on off-the-shelf hardware and open-source operating systems running on the personal-computer (PC) architecture. Today's high-end PCs are equipped with peripheral component interconnect (PCI) shared buses enabling them to easily fit into the multi-gigabit-per-second routing(More)
BACKGROUND Atrial fibrillation has a high incidence in patients wearing an implantable cardioverter defibrillator for ventricular tachyarrhythmias and may lead to palpitations, heart failure, angina, stroke and inappropriate defibrillator discharge. The aim of the study was to evaluate the efficacy of a dual chamber defibrillator with atrial antitachycardia(More)
AIMS Atrial fibrillation (AF) is a common comorbidity in bradycardia patients. Advanced pacemakers feature atrial preventive pacing and atrial antitachycardia pacing (DDDRP) and managed ventricular pacing (MVP), which minimizes unnecessary right ventricular pacing. We evaluated whether DDDRP and MVP might reduce mortality, morbidity, or progression to(More)
AIMS To evaluate clinical and arrhythmic outcomes in post-infarction cardiomyopathy patients implanted with a defibrillator (ICD) for primary prevention of sudden death. METHODS AND RESULTS The SEARCH-MI registry is a European multi-centre, prospective, observational study enrolling patients after myocardial infarction, chronic left ventricular(More)
AIMS To analyse the effectiveness of cardiac resynchronization therapy (CRT) in patients with valvular heart disease (a subset not specifically investigated in randomized controlled trials) in comparison with ischaemic heart disease or dilated cardiomyopathy patients. METHODS AND RESULTS Patients enrolled in a national registry were evaluated during a(More)
Fingolimod is a sphingosine 1-phosphate (S1P) receptor modulator approved to treat relapsing-remitting multiple sclerosis (MS). Initiation of treatment with fingolimod has been found to produce transient bradycardia and/or slowing of atrioventricular impulse conduction in a small proportion of patients. This effect is thought to be due to the interaction of(More)
BACKGROUND A multicenter European Registry, SEARCH-MI, was instituted in the year 2002 in order to assess patients' outcomes and ICD interventions in patients with a previous MI and depressed LV function, treated with an ICD according to MADIT II results. In this analysis, we evaluate the influence of the time elapsed between last myocardial infarction (MI)(More)
  • P F Bertoluzza, N Cova, P Delmonte, M Pampili, Portesine, A Pirondi +27 others
  • 2012
Coupled measurement-simulation procedure for very high power fast recovery – soft behavior diode design and testing " , Microelectronics Reliability, Thermo-mechanical simulation of a multichip press-packed IGBT " , Finite element design of water heat sinks for press-pack IGBTs " , Proc. A new silicon resistor technology for very high power snubbers " ,(More)