Giampaolo Lavagetto

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Clinical observations indicate that elderly people are prone to severe, often lethal infectious diseases induced by novel pathogens. Since the ability to mount primary immune responses relies on the availability of naive T cells, the circulating naive T-cell reservoir was evaluated throughout the human life span. Naive T cells were identified as CD95(-) T(More)
Ageing is associated with complex remodelling in the phenotypic and functional profiles of T lymphocytes. We investigated whether expression of CD28 antigen on T cells is conserved throughout adulthood and ageing in humans. For this purpose we analysed T cells obtained from peripheral blood of 102 healthy people of ages ranging from 20 to 105 years. We(More)
It is generally assumed that T cell proliferation is impaired in aged individuals. We report data on the proliferative capability of peripheral blood mononuclear cells (PBMC) and T lymphocytes from 40 healthy people of different ages, (19-107 years), including 14 centenarians, to defined mitogenic stimuli. We observed no age-related proliferative impairment(More)
We present a precise timing analysis of the accreting millisecond pulsar XTE J1814– 338 during its 2003 outburst, observed by RXTE. A full orbital solution is given for the first time; Doppler effects induced by the motion of the source in the binary system were corrected, leading to a refined estimate of the orbital period, Porb = 15388.7229(2) s, and of(More)
We study the broad band (3-100 keV) spectrum of Cygnus X–2 with INTEGRAL. We find that the spectrum is well fitted by a Comptonized component with a seed-photons temperature of ∼ 1 keV, an electron temperature of ∼ 3 keV and an optical depth τ ∼ 8. Assuming spherical geometry, the radius of the seed-photons emitting region is ∼ 17 km. The source shows no(More)
The recent discovery of burst oscillations at 1122 Hz in the x-ray transient XTE J1739-285, together with the measurement of the mass of the binary millisecond pulsar PSR J0751+1807 (2.1± 0.2 M⊙) can finally allow us to put strong, model-independent observational constraints to the equation of state of compact stars. We show that the measurement of the(More)
Aims. We present the results of the analysis of an archival observation of LMC X–2 performed with XMM/Newton. The spectra taken by high-precision instruments have never been analyzed before. Methods. We find an X–ray position for the source that is inconsistent with the one obtained by ROSAT, but in agreement with the Einstein position and that of the(More)
We performed a timing analysis of the 2003 outburst of the accreting X-ray millisecond pulsar XTE J1807–294 observed by RXTE. Using recently refined orbital parameters we report for the first time a precise estimate of the spin frequency and of the spin frequency derivative. The phase delays of the pulse profile show a strong erratic behavior superposed to(More)
Clinical observations indicate that elderly people are prone to severe, often lethal infectious diseases induced by novel pathogens. Since the ability to mount primary immune responses relies on the availability of naive T cells, the circulating naive T-cell reservoir was evaluated throughout the human life span. Naive T cells were identified as CD952 T(More)
We report on the serendipitous discovery of a new X-ray source, SAX J1802.7– 2017, ∼ 22 away from the bright X-ray source GX 9+1, during a BeppoSAX observation of the latter source on 2001 September 16–20. SAX J1802.7–2017 remained undetected in the first 50 ks of observation; the source count rate in the following ∼ 300 ks ranged between 0.04 c/s and 0.28(More)