Giambattista Guaitoli

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Acquired resistance to cisplatin (cDDP) is a multifactorial process that represents one of the main problems in ovarian cancer therapy. Distamycin A is a minor groove DNA binder whose toxicity has limited its use and prompted the synthesis of derivatives such as NAX001 and NAX002, which have a carbamoyl moiety and different numbers of pyrrolamidine groups.(More)
The European Commission estimates that car crash-related costs in Europe are around 160 billion euros, approximately 2% of the Gross Domestic Product [1]. In several countries, car crashes are the first cause of death among subjects aged 15-30, with a direct heavy impact on the years of life lost; in young subjects car crashes also represent one of the(More)
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