Giacomo Savini

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BACKGROUND To evaluate the influence of axial length on measurements of the retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) parameters in healthy subjects. METHODS Using Cirrus HD-OCT, RNFL thickness and ONH parameters (disc and rim area) were measured in 15 short (<22.5 mm), 15 medium (22.51-25.5 mm) and 15 long (>25.51 mm) eyes. (More)
1 Istituto Scientifico San Raffaele, Milano, Italy 2 Studio Oculistico d’Azeglio, Bologna, Italy 3 IRCCS, Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy 4 Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy 5 IRCCS Fondazione Bietti, Roma, Italy 6 Doheny Eye Institute and Department of(More)
PURPOSE To assess the repeatability of the anterior segment measurements performed with a dual Scheimpflug analyzer (Galilei) in unoperated and post-refractive surgery eyes. SETTING Private practice. DESIGN Evaluation of diagnostic test. METHODS Three consecutive scans were acquired in unoperated eyes and in eyes that had excimer laser surgery for(More)
Optic neuropathy is common in mitochondrial disorders, but poorly characterized in Friedreich's ataxia (FRDA), a recessive condition caused by lack of the mitochondrial protein frataxin. We investigated 26 molecularly confirmed FRDA patients by studying both anterior and posterior sections of the visual pathway using a new, integrated approach. This(More)
PURPOSE To investigate by optical coherence tomography (OCT) the topographic pattern and temporal sequence of fiber loss in the peripapillary retinal nerve fiber layer (RNFL) of patients with Leber's hereditary optic neuropathy (LHON) in a longitudinal follow-up. DESIGN Cohort study. PARTICIPANTS Six eyes of 4 patients with molecularly defined LHON were(More)
PURPOSE To study retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT) in unaffected carriers with Leber's hereditary optic neuropathy (LHON) mutations. DESIGN Cross-sectional study. PARTICIPANTS Sixty-six unaffected carriers (44 females and 22 males) were analyzed and compared with an age-matched control group of 70 patients(More)
OBJECTIVE To evaluate the reliability of different methods developed to calculate intraocular lens (IOL) power after corneal refractive surgery. DESIGN Retrospective observational case series. PARTICIPANTS Preoperative and postoperative data of all eyes that underwent myopic excimer laser surgery in a private practice (Centro Salus, Bologna, Italy)(More)
PURPOSE To assess the repeatability and reproducibility of 3 rotating Scheimpflug cameras, the Pentacam (Oculus, Wetzlar, Germany), Sirius (Costruzione Strumenti Oftalmici, Florence, Italy), and Galilei (Ziemer, Biel, Switzerland), and 1 Fourier-domain optical coherence tomography (FD-OCT) system, the RTvue-100 OCT (Optovue Inc., Fremont, CA), in measuring(More)
PURPOSE To comprehensively assess the precision and agreement of anterior corneal power measurements using 8 different devices. METHODS Thirty-five eyes from 35 healthy subjects were included in the prospective study. In the first session, a single examiner performed on each subject randomly measurements with the RC-5000 (Tomey Corp., Japan), KR-8000(More)
OBJECTIVE To investigate the ability of optical coherence tomography (OCT) to assess changes in retinal nerve fiber layer (RNFL) thickness in optic disc edema. METHODS Prospective observational case series in a private eye clinic (Centro Salus). Twelve consecutive eyes (9 patients) with optic disc edema were analyzed, including 6 patients with anterior(More)