Gholam Reza Kheirabadi

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BACKGROUND Childbearing years in the women's life are associated with the highest risk of depression. In this study depression in third trimester of pregnancy and after delivery was studied. Depressive symptom score and the proportion of mothers above a threshold were compared to indicate probable depressive disorder at each stage. METHODS This(More)
BACKGROUND Edinburgh Postnatal Depression Scale (EPDS) has been used as a reliable screening tool for postpartum depression in many countries. This study aimed to assess the psychometric properties and diagnostic accuracy of the EPDS in a sample of Iranian women. METHODS Using stratified sampling 262 postpartum women (2 weeks-3 months after delivery) were(More)
AIMS Evaluation of the efficacy of gabapentin in patients undergoing out-patient treatment for opiate withdrawal. DESIGN A 3-week double-blind, randomized, placebo-controlled trial of adjunctive gabapentin in methadone-assisted detoxification (MAD). SETTING Specialized Addictive Behaviors Unit, an out-patient unit for the treatment of patients with an(More)
BACKGROUND Methamphetamine (METH) abuse and dependence present a major global problem. We investigated the efficacy of adding buprenorphine in reducing METH cravings during treatment with the Matrix program. METHODS This was a randomized, double-blind, controlled clinical trial of 40 men between the age of 18 and 40 years who were referred to the(More)
AIM The aim of the study was to evaluate the efficacy of gabapentin (1600 mg/d) as an adjunctive to methadone-assisted detoxification in the treatment of opioid withdrawal symptoms. DESIGN This was a 3-week open-label study (as second phase) following a double-blind, placebo-controlled study with 900 mg/d of gabapentin (as first phase of this study). (More)
BACKGROUND There are situations in every woman's life that impressively affect her whole life. Pregnancy is one of those situations. Pregnancy period is usually accompanied with positive emotions for the women and their families. Sometimes depression during pregnancy disturbs daily activities, acceptance of new roles, pregnant woman΄s life responsibilities(More)
BACKGROUND Quality of life (QOL) improvement is the main objective of treating patients with irritable bowel syndrome (IBS). This study aimed to assess the validity, reliability, and factor analysis of IBS-QOL-34 questionnaire as a common transcultural instrument for Iranian IBS patients. MATERIALS AND METHODS Two hundred and forty patients with IBS(More)
BACKGROUND Methamphetamine dependence lead to the compulsive use, loss of control, and social and occupational dysfunctions. This study aimed to compare the effect of valproate in reducing the craving in methamphetamine dependents. MATERIALS AND METHODS This is a randomized, double-blind, controlled clinical trial on 40 men of 18-40 years old referred to(More)
CONTEXT Exact measurement of quality of life (QOL) in schizophrenia patients for evaluation of the patient's deterioration and also to assess the efficacy of therapeutic Interventions has become a daily task, which requires accurate assessment tools. AIMS This study was aimed to assess the psychometric properties of a Persian version of schizophrenia QOL(More)
BACKGROUND Studies have shown the association of mood disorders and endothelial dysfunction, and increased risk of cardiovascular disease; however, mediatory mechanisms are not entirely clarified in this regard. We investigated the relationship between depression/anxiety symptoms with systemic inflammation and endothelial function. MATERIALS AND METHODS(More)