Gholam Hassan Haddadi

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OBJECTIVE Free radicals generated by ionizing radiation attack various cellular components such as lipids. The lung is a very radiosensitive organ and its damage is a doselimiting factor in radiotherapy treatments. Melatonin (MLT), the major product of the pineal gland acts as a radioprotective agent. This study aims to investigate the radioprotective(More)
BACKGROUND Radiotherapy of the thorax often causes lung inflammation leading to fibrosis. OBJECTIVES The aim of this study was to investigate whether the use of glycyrrhizic acid (GLA) could improve the development of lung fibrosis in irradiated animals. MATERIALS AND METHODS Wistar rats were divided into four groups. Group A rats received thoracic(More)
This study was carried out to evaluate radioprotective effects of hesperidin (HES) administration before the irradiation on the cardiac oxidative stress and histopathological changes in an experimental rat model. The cardiovascular complications of radiation exposure cause morbidity and mortality in patients who received radiotherapy. HES, an antioxidant(More)
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