Gheorghe Manole

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The protein encoded by the NCE103 gene of Candida glabrata, a beta-carbonic anhydrase (CA, EC designated as CgCA, was investigated for its activation with amines and amino acids. CgCA was(More)
N-4-Nitrobenzyl-beta-alanine was reacted with alkyl/arylsulfonyl halides, followed by conversion of the COOH to the CONHOH group. Structurally related compounds were obtained by reaction of(More)
A series of heterocyclic mercaptans incorporating 1,3,4-thiadiazole- and 1,2,4-triazole rings have been prepared and assayed for the inhibition of three physiologically relevant carbonic anhydrase(More)