Ghayath Baroudi

Learn More
T waves in the human electrocardiogram generally have the same sign as QRS complexes (T-wave concordance). Heterogeneity of the slow delayed rectifier current (I Ks) is often held responsible for this. We demonstrate that this idea is in conflict with the observation of relatively large T-wave amplitude in patients with the long-QT type 1 syndrome. Another(More)
INTRODUCTION Recent studies revealed that co-morbidity and mortality due to cardiovascular disease are increased in patients with rheumatoid arthritis (RA) but little is known about factors involved in these manifestations. This study aimed at characterizing the impact of arthritis on oxidative stress status and tissue fibrosis in the heart of rats with(More)
Protein kinases C (PKC) modulate the activity of the Kv11.1 ion channel current (hERG). However, the differential effects of specific PKC subtypes on the biophysics of the channel are unknown. The pharmaceutical tools to selectively modulate PKC subtypes are not membrane permeable and must be added directly to the intracellular solution in electrophysiology(More)
about our recent study [2] and would like to make two points to clarify our reasoning. First, in our study [2], female Lewis rats have been used in order to induce arthritis. Th is experimental model of arthritis was well described in our previous study published in Molecular Th erapy [3]. Actually, a number of researchers use male or female animals to(More)
  • 1