Ghanshyam M. Kotadiya

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A rational approach was adopted for the synthesis of 1-(2-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)-3-(aryl)prop-2-en-1-ones (5a–n) using conventional heating as well as microwave irradiation techniques. Compounds 5a–n were tested for their in vitro antimicrobial activity and cytotoxicity. Compounds 5g showed(More)
A new series of 1-(2-(3-(4-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)-3-(aryl)prop-2-en-1-ones (5a–l) were synthesized by a simple and efficient synthetic protocol. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR and Mass spectroscopy. The resulting structural diversity was screened for its(More)
A series of 6-(1H-benzo[d]imidazol-2-yl)-2-(2-(3-nitrophenyl)-4-oxothiazolidin-yl)-4-(aryl)nicotinonitriles 5a–l were synthesized and characterized by IR, 1H NMR, 13C NMR, and mass spectrometry techniques. These novel compounds 5a–l were screened for their in vitro antimicrobial activity against different bacterial and fungal strains and in vitro(More)
A rational approach was adopted for the synthesis of novel series of 1-(2-(1H-benzo[d]imidazol-2-yl)-2-methyl-5-aryl-1,3,4-oxadiazol-3(2H)-yl)-3-(4-chlorophenyl)prop-2-en-1-ones 5a–n under microwave irradiation technique. Synthesized compounds were tested for their in vitro antimicrobial activity against Gram-positive, Gram-negative strains of bacteria as(More)
A new series of compounds N-(4-(2-(3-(1H-benzo[d]imidazol-2-yl)-5-(aryl)-4,5-dihydro-1H-pyrazol-1-yl)-2-oxoethoxy)phenyl)acetamides (5a–u) were synthesized and structures of these compounds were elucidated by spectral (IR, 1H NMR, 13C NMR, and mass spectra) analysis. Antimicrobial activity was measured against Escherichia coli (MTCC 443), Pseudomonas(More)
In the present study, a series of novel 6-(1H-benzo[d]imidazol-2-yl)-2-(3-chloro-2-oxo-4-phenylazetidin-1-yl)-4-(aryl)nicotinonitriles 6a–o were efficiently synthesized and evaluated for their in vitro antibacterial activity against Gram-positive (Staphylococcus aureus and Streptococcus pyogenes), Gram-negative (Escherichia coli and Pseudomonas aeruginosa)(More)
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