Learn More
The hippocampus produces growth hormone (GH) and contains GH receptors, suggesting a potential role for GH signaling in the regulation of hippocampal function. In agreement with this possibility, previous investigations have found altered hippocampal function and hippocampal-dependent learning and memory after chronic GH administration or deficiency. In(More)
Rapid eye movement (REM) sleep deprivation has previously been shown to interfere with normal learning and memory and to inhibit long-term potentiation (LTP) in vitro. Previous studies on REM sleep deprivation and LTP have relied on in vitro analysis in isolated brain slices taken from animals following several days of sleep deprivation. LTP in the(More)
Background. Hypothyroidism is considered as one of the most common of all endocrine diseases. The risk of cardiovascular disease is markedly increased with hypothyroidism. Garcinia cambojia (GC/HCA) is one of the commonly used natural products for losing weight and correcting lipid profile. Goals. To investigate the efficacy and safety of GC/HCA in(More)
OBJECTIVES This in vitro study aimed to investigate the possible mechanism underlying the protective effect of growth hormone (GH) on hippocampal function during periods of heightened glucocorticoid exposure. METHODS This study was conducted between January and June 2005 at the Joan C. Edwards School of Medicine, Marshall University, in Huntington, West(More)
Growth hormone enhances excitatory synaptic transmission in area CA1 of rat hippocampus. The hippocampus produces growth hormone (GH) and contains GH receptors, suggesting a potential role for GH signaling in the regulation of hippocampal function. In agreement with this possibility, previous investigations have found altered hippocampal function and(More)
  • 1