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A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips.

• Carl Fredrik Carlborg, Kristinn B. Gylfason, +12 authors Wouter van der Wijngaart
• Lab on a chip
• 2010

We present the design, fabrication, and characterisation of an array of optical slot-waveguide ring resonator sensors, integrated with microfluidic sample handling in a compact cartridge, for… (More)

PCR on a PDMS-based microchip with integrated bubble removal

• Joel Karlsson, Tommy Haraldsson, +4 authors Wouter van der Wijngaart
• 16th International Solid-State Sensors, Actuators…
• 2011

We report on the successful manufacturing and operation of the first PDMS-based PCR microreactor with continuous on-chip debubbling. A semipermeable membrane between the PCR chamber and a… (More)

Insight into early events in the aggregation of the prion protein on lipid membranes.

• Narinder Sanghera, Marcus J. Swann, Gerry Ronan, Teresa T. J. Pinheiro
• Biochimica et biophysica acta
• 2009

The key molecular event underlying prion diseases is the conversion of the monomeric and alpha-helical cellular form of the prion protein (PrP(C)) to the disease-associated state, which is aggregated… (More)

Quantification of the effects of melittin on liposome structure.

• Jonathan Popplewell, Neville J Freeman, Simon Carrington, Gerry Ronan, Ciaran McDonnell, Robert Curtis Ford
• Biochemical Society transactions
• 2005

An optical technique, dual-polarization interferometry, has been used to examine lipid structures at the solid/liquid interface. Changes in the lipid structures, in real time, were examined as a… (More)

Microfluidic and transducer technologies for lab on a chip applications

• Davion Hill, Niklas Sandstrom, +18 authors Wouter van der Wijngaart
• Annual International Conference of the IEEE…
• 2010

Point-of-care diagnostic devices typically require six distinct qualities: they must deliver at least the same sensitivity and selectivity, and for a cost per assay no greater than that of today's… (More)

Quantifying structural changes and stoichiometry of protein interactions using size and density profiling

• Marcus J. Swann, Neville J Freeman, Simon Carrington, Gerry Ronan, Paul Barrett
• Letters in Peptide Science
• 2004

The use of Dual Polarisation Interferometry, an emerging analytical biophysical technique, is described for the determination of the optogeometrical properties (thickness and density) at high… (More)

Molecular imaging and orientational changes of antimicrobial peptides in membranes.

• T H Lee, Kristopher N. Hall, +4 authors Marie-isabel Aguilar
• Advances in experimental medicine and biology
• 2009

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