German Konovalov

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A study was made of the development of the brain from 44 embryos (5-12 weeks) and 1 fetus (14 weeks) obtained from mothers who used alcohol during pregnancy. 16 cases made up the control group. In 34 cases out of 45 (75.5%), deviations in the development of the brain were established and distributed into the three degrees of gravity: mild, moderate and(More)
On 62 white male rats at hypokinesia lasting for 7-60 days, motoneurons and neural cells of the lumbar sensitive ganglia have been studied at the level of L2--L4. Certain changes in the spinal ganglia have been neurohistologically revealed beginning from the 30th day of the experiment. In most of the neurons, mainly in large ones, phenomena of central(More)
A combined comparative virological, morphological, and immunological study of experimental coronavirus encephalomyelitis was carried out in mice in order to elucidate the pathogenetic mechanisms involved in the formation of the foci of lesions in acute and chronic forms of the disease. Intracerebral inoculation of C3H mice with the neurotropic JHM strain of(More)
The effect of various ethanol concentrations (0.5 and 1%) on the ultrastructure of interneouronal contacts is studied in an organotypic culture of the brain cortex from newborn rats. It is shown that ethanol in the culture medium causes geometric complications in the synaptic contacts. Morphometric analysis of synapses reveals an increase of the area and(More)
Morpho-functional development of the cerebral cortex of newborn rats and the influence of noradrenaline (NA) on this process was investigated under the conditions of long-term (up to 41 days) organotypical tissue cultivation. Systematic adding of NA to the nutrient medium in the process of explants cultivation was shown to disturb its structural(More)
The paper deals with morpho-functional development of the visual area of newborn rats cerebral cortex in conditions of prolonged (up to 40 days) organotypical cultivation and with the effect of serotonin (5-OT) on these processes. It has been shown that systematic addition of physiological concentrations of 5-OT to the nutrient medium during explantates(More)
The authors present the results of studying encephalomyelitis caused by the neurotropic (IHM) strain of the murine hepatitis virus in 60 mice of the C3H line infected intracerebrally at the age of 4 weeks. Morphological examinations of the brain carried out on the 5th-13th day (the acute period) and the 14th-30th day (the subacute stage) have shown that it(More)