Gerlinde Debus

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PURPOSE To evaluate the use of clinical 1.5-T magnetic resonance (MR) imaging equipment to depict the in vivo distribution of iron oxide-labeled human hematopoietic progenitor cells in athymic mice. MATERIALS AND METHODS This study was approved by the ethical committee, and all women had given consent to donate umbilical cord blood for research. Twenty(More)
BACKGROUND Pretreatment cognitive impairment in cancer patients is well established but unexplained. Similar cognitive compromise has been observed in post-traumatic stress disorder (PTSD) patients, and PTSD symptoms are a frequent concomitant of cancer diagnosis. We tested the hypothesis that pretreatment cognitive impairment is attributable to(More)
Mobilization and recruitment of endothelial progenitor cells (EPC) contributes to vasculogenesis in vivo. So far, applications for cell therapy are limited by the number of available cells. Expansion of EPC or their progeny may, therefore, facilitate its therapeutic use in ischemic disease. The aim of this study was to expand CD34+ EPC-derived progeny from(More)
The combined effects of oxazolam (Tranquit), a benzodiazepine, and alcohol were examined in two separate studies. 20 healthy male student subjects participated in study I. 20 mg and 60 mg of oxazolam and placebo were combined with 0.55 g/kg alcohol and alcohol placebo. There were 3-4 subjects in each of the six cells of the 3 X 2 design. 102 healthy male(More)
The results of a pharmacopsychological study on male students high or low in emotional stability are compared to those of a clinical study on neurotic out- and inpatients. These studies examine the effects of diazepam and various doses of a thienodiazepine (Bay g 5653), a drug under investigation. Although the studies are not completely comparable (placebo(More)
OBJECTIVE There is ongoing debate whether cancer qualifies as traumatic stressor. We investigated prevalence and course of posttraumatic stress in patients with early breast cancer (BC) during their first year after diagnosis and determined effects of mastectomy and chemotherapy. METHODS Patients with stage 0-III BC aged ≤65 years were evaluated with the(More)