Gerhard M. Kostner

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High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.

Wolfgang F. Graier, S Simecek, Walter R. Kukovetz, Gerhard M. Kostner
Diabetes
1996

Pretreatment of porcine aortic endothelial cells with high D-glucose results in enhanced endothelium-derived relaxing factor (EDRF) formation (39%) due to increased endothelial Ca2+ release (57%) and… (More)

Solution structure of human and bovine beta(2)-glycoprotein I revealed by small-angle X-ray scattering.

Michal Hammel, Manfred Kriechbaum, Anna Gries, Gerhard M. Kostner, Peter Laggner, Ruth Prassl
Journal of molecular biology
2002

beta(2)-Glycoprotein I (beta(2)GPI) is a highly glycosylated phospholipid-binding plasma protein comprised of four complement control protein (CCP) domains and a distinct fifth domain. The structural… (More)

Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution.

E. Fleischhacker, Victor E Esenabhalu, +5 authors Wolfgang F. Graier
Diabetes
1999

Alterations of vascular smooth muscle function have been implicated in the development of vascular complications and circulatory dysfunction in diabetes. However, little is known about changes in… (More)

Undifferentiated human mesenchymal stem cells (hMSCs) are highly sensitive to mechanical strain: transcriptionally controlled early osteo-chondrogenic response in vitro.

Gerald Friedl, Harald Schmidt, Ivan Rehák, Gerhard M. Kostner, Konrad Schauenstein, Reinhard Windhager
Osteoarthritis and cartilage
2007

OBJECTIVE Physical cues play a crucial role in skeletogenesis and osteochondral regeneration. Although human mesenchymal stem cells (hMSCs) offer considerable therapeutic potential, little is known… (More)

Correlation of hormones with lipid and lipoprotein levels during normal pregnancy and postpartum.

Gernot Desoye, Meinhardt O. Schweditsch, Karl Peter Pfeiffer, Rudolf Zechner, Gerhard M. Kostner
The Journal of clinical endocrinology and…
1987

In a comprehensive study the concentrations of plasma lipids and lipo- and apolipoproteins were measured in 24 nonpregnant women (control) and longitudinally in 42 women throughout gestation and… (More)

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo.

Frank M. Sacks, Lawrence Lee Rudel, +11 authors Hollis B Brewer
Journal of lipid research
2009

Uptake of cholesterol from peripheral cells by nascent small HDL circulating in plasma is necessary to prevent atherosclerosis. This process, termed reverse cholesterol transport, produces larger… (More)

Human plasma phospholipid transfer protein accelerates exchange/transfer of alpha-tocopherol between lipoproteins and cells.

Gerhard M. Kostner, Karl Oettl, Matti S Jauhiainen, Christian P Ehnholm, Harald Esterbauer, Hans Dieplinger
The Biochemical journal
1995

alpha-Tocopherol (alpha-T), an important anti-oxidant of plasma lipoproteins and cell membranes, is secreted from liver together with very-low-density lipoproteins into the blood stream. Other serum… (More)

Urinary excretion of apo(a) fragments. Role in apo(a) catabolism.

Karam Maximilien Kostner, Gerald Maurer, +4 authors Gerhard M. Kostner
Arteriosclerosis, thrombosis, and vascular…
1996

The biosynthesis and assembly of lipoprotein(a) [Lp(a)], a marker for atherosclerotic disease, appears to be well understood. However, information is lacking concerning the mode and site of Lp(a)… (More)

When should we measure lipoprotein (a)?

Karam Maximilien Kostner, Winfried Maerz, Gerhard M. Kostner
European heart journal
2013

Recently published epidemiological and genetic studies strongly suggest a causal relationship of elevated concentrations of lipoprotein (a) [Lp(a)] with cardiovascular disease (CVD), independent of… (More)

Adenovirus-mediated rescue of lipoprotein lipase-deficient mice. Lipolysis of triglyceride-rich lipoproteins is essential for high density lipoprotein maturation in mice.

Juliane Gertrude Strauss, Steffanie Frank, +6 authors Rudolf Zechner
The Journal of biological chemistry
2001

Lipoprotein lipase (LPL) is the rate-limiting enzyme for the hydrolysis of triglycerides and the subsequent uptake of free fatty acids in extrahepatic tissues. Deficiency of LPL in humans (Type I… (More)

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